2016

Aguiar PM, da Silva CH, Chiann C, Dórea EL, Lyra DP Jr, Storpirtis S. Pharmacist-physician collaborative care model for patients with uncontrolled type 2 diabetes in Brazil: results from a randomized controlled trial. J Eval Clin Pract. 2016 Jul 25.

Albuquerque AF, Queiroz SI, Germano AR, da Silva JS. Factors associated to post-operative nausea and vomiting following oral and maxillofacial surgery: a prospective study. Oral Maxillofac Surg. 2016 Nov 30.

Alves-Filho JC, Pålsson-McDermott EM. Pyruvate Kinase M2: A Potential Target for Regulating Inflammation. Front Immunol. 2016 Apr 21;7:145.

Alves-Lopes R, Neves KB, Montezano AC, Harvey A, Carneiro FS, Touyz RM, Tostes RC. Internal Pudental Artery Dysfunction in Diabetes Mellitus Is Mediated by NOX1-Derived ROS-, Nrf2-, and Rho Kinase-Dependent Mechanisms. Hypertension. 2016 Oct;68(4):1056-64.

Alves-Lopes R, Neves KB, Silva MA, Olivon VC, Ruginsk SG, Antunes-Rodrigues J, Ramalho LN, Tostes RC, Carneiro FS. Functional and structural changes in internal pudendal arteries underlie erectile dysfunction induced by androgen deprivation. Asian J Androl. 2016 Jul 5.

Antunes-Correa LM, Ueno-Pardi LM, Trevizan PF, Santos MR, da Silva CH, Franco FG, Alves MJ, Rondon MU, Negrao CE. The influence of aetiology on the benefits of exercise training in patients with heart failure. Eur J Prev Cardiol. 2016 Dec 12.

Araujo GR, Fujimura PT, Vaz ER, Silva TA, Rodovalho VR, Britto-Madurro AG, Madurro JM, Fonseca JE, Silva CH, Santos PS, Mourão AF, Canhão H, Goulart LR, Gonçalves J, Ueira-Vieira C. A novel reactive epitope-based antigen targeted by serum autoantibodies in oligoarticular and polyarticular juvenile idiopathic arthritis and development of an electrochemical biosensor. Immunobiology. 2016 May;221(5):634-40.

Araújo PP, Sousa SA, Diniz VB, Gomes PP, da Silva JS, Germano AR. Evaluation of patients undergoing placement of zygomatic implants using sinus slot technique. Int J Implant Dent. 2016 Dec;2(1):2.

Ayres C, Ferreira CF, Bernardi JR, Marcelino TB, Hirakata VN, Silva CH, Goldani MZ. A method for the assessment of facial hedonic reactions in newborns. J Pediatr (Rio J). 2016 Nov 23.

Bassi GS, do C Malvar D, Cunha TM, Cunha FQ, Kanashiro A. Spinal GABA-B receptor modulates neutrophil recruitment to the knee joint in zymosan-induced arthritis. Naunyn Schmiedebergs Arch Pharmacol. 2016 Aug;389(8):851-61.

Bazot M, Bharwani N, Huchon C, Kinkel K, Cunha TM, Guerra A, Manganaro L, Buñesch L, Kido A, Togashi K, Thomassin-Naggara I, Rockall AG. European society of urogenital radiology (ESUR) guidelines: MR imaging of pelvic endometriosis. Eur Radiol. 2016 Dec 5.

Bonati PC, Silva CH. Erratum to “Childhood respiratory viruses in public health care centers”. Braz J Infect Dis. 2016 Nov – Dec;20(6):651.

Bradley WP, Boyer MA, Nguyen HT, Birdwell LD, Yu J, Ribeiro JM, Weiss SR, Zamboni DS, Roy CR, Shin S. Primary Role for Toll-Like Receptor-Driven Tumor Necrosis Factor Rather than Cytosolic Immune Detection in Restricting Coxiella burnetii Phase II Replication within Mouse Macrophages. Infect Immun. 2016 Mar 24;84(4):998-1015.

Brito MF, Ferreira JV, Souza LR, Gemaque LR, Sousa KP, Santos CF, Braga FS, Pernomian L, Silva CH, Santos CB. Taft CA, Hage-Melim LI. Computational Molecular Modeling of Compounds from Amaryllidaceae Family as Potential Acetylcholinesterase Inhibitors. Current Bioactive Compounds, 2016.

Bruder-Nascimento T, Callera G, Montezano AC, Antunes TT, He Y, Cat AN, Ferreira NS, Barreto PA, Olivon VC, Tostes RC, Touyz RM. Renoprotective Effects of Atorvastatin in Diabetic Mice: Downregulation of RhoA and Upregulation of Akt/GSK3. PLoS One. 2016 Sep 20;11(9):e0162731.

Bruder-Nascimento T, Ferreira NS, Zanotto CZ, Ramalho F, Pequeno IO, Olivon VC, Neves KB, Alves-Lopes R, Campos E, Silva CA, Fazan R, Carlos D, Mestriner FL, Prado D, Pereira FV, Braga T, Luiz JP, Cau SB, Elias PC, Moreira AC, Câmara NO, Zamboni DS, Alves-Filho JC, Tostes RC. NLRP3 Inflammasome Mediates Aldosterone-Induced Vascular Damage. Circulation. 2016 Dec 6;134(23):1866-1880.

Bueno-Silva B, Franchin M, Alves CF, Denny C, Colón DF, Cunha TM, Alencar SM, Napimoga MH, Rosalen PL. Main pathways of action of Brazilian red propolis on the modulation of neutrophils migration in the inflammatory process. Phytomedicine. 2016 Dec 1;23(13):1583-1590.

Caliari-Oliveira C, Yaochite JN, Ramalho LN, Palma PV, Carlos D, Cunha Fde Q, De Souza DA, Frade MA, Covas DT, Malmegrim KC, Oliveira MC, Voltarelli JC. Xenogeneic Mesenchymal Stromal Cells Improve Wound Healing and Modulate the Immune Response in an Extensive Burn Model. Cell Transplant. 2016;25(2):201-15.

Carregaro V, Napimoga MH, Peres RS, Benevides L, Sacramento LA, Pinto LG, Grespan R, Cunha TM, da Silva JS, Cunha FQ. Therapeutic Treatment of Arthritic Mice with 15-Deoxy Δ(12,14)-Prostaglandin J(2) (15d-PGJ(2)) Ameliorates Disease through the Suppression of Th17 Cells and the Induction of CD4(+)CD25(-)FOXP3(+) Cells. Mediators Inflamm. 2016;2016:9626427.

Cavalcanti CA, Silva Jde A, Pita Wde B, Veit TD, Monticielo OA, Xavier RM, Brenol JC, Brenol CV, Fragoso TS, Barbosa AD, Duarte ÂL, Oliveira RD, Louzada-Júnior P, Donadi EA, Crovella S, Chies JA, Sandrin-Garcia P. Vitamin D receptor polymorphisms and expression profile in rheumatoid arthritis Brazilian patients. Mol Biol Rep. 2016 Jan;43(1):41-51.

Chaves de Souza JA, Frasnelli SC, Curylofo-Zotti FA, Ávila-Campos MJ, Spolidório LC, Zamboni DS, Graves DT, Rossa C Jr. NOD1 in the modulation of host-microbe interactions and inflammatory bone resorption in the periodontal disease model. Immunology. 2016 Dec;149(4):374-385.

Cittolin-Santos GF, de Assis AM, Guazzelli PA, Paniz LG, da Silva JS, Calcagnotto ME, Hansel G, Zenki KC, Kalinine E, Duarte MM, Souza DO. Guanosine Exerts Neuroprotective Effect in an Experimental Model of Acute Ammonia Intoxication. Mol Neurobiol. 2016 Apr 6.

Coimbra FC, Salles MM, De Oliveira VC, Macedo AP, Da Silva CH, Pagnano VO, Paranhos Hde F. Antimicrobial efficacy of complete denture cleansers. Am J Dent. 2016 Jun;29(3):149-53.

Costa FR, Françozo MC, de Oliveira GG, Ignacio A, Castoldi A, Zamboni DS, Ramos SG, Câmara NO, de Zoete MR, Palm NW, Flavell RA, Silva JS, Carlos D. Gut microbiota translocation to the pancreatic lymph nodes triggers NOD2 activation and contributes to T1D onset. J Exp Med. 2016 Jun 27;213(7):1223-39.

Costa RM, Filgueira FP, Tostes RC, Carvalho MH, Akamine EH, Lobato NS. H2O2 generated from mitochondrial electron transport chain in thoracic perivascular adipose tissue is crucial for modulation of vascular smooth muscle contraction. Vascul Pharmacol. 2016 Sep;84:28-37.

Czaikoski PG, Mota JM, Nascimento DC, Sônego F, Castanheira FV, Melo PH, Scortegagna GT, Silva RL, Barroso-Sousa R, Souto FO, Pazin-Filho A, Figueiredo F, Alves-Filho JC, Cunha FQ. Neutrophil Extracellular Traps Induce Organ Damage during Experimental and Clinical Sepsis. PLoS One. 2016 Feb 5;11(2):e0148142.

da Costa RM, Fais RS, Dechandt CR, Louzada-Junior P, Alberici LC, Lobato NS, Tostes RC. Increased mitochondrial ROS generation mediates the loss of PVAT anticontractile effect in HFD-treated obese mice. Br J Pharmacol. 2016 Dec 8.

da Costa RM, Neves KB, Mestriner FL, Louzada-Junior P, Bruder-Nascimento T, Tostes RC. TNF-α induces vascular insulin resistance via positive modulation of PTEN and decreased Akt/eNOS/NO signaling in high fat diet-fed mice. Cardiovasc Diabetol. 2016 Aug 25;15(1):119.

da Silva CH, Taft CA. 3D descriptors calculation and conformational search to investigate potential bioactive conformations, with application in 3D-QSAR and virtual screening in drug design. J Biomol Struct Dyn. 2016 Oct 14:1-9.

da Silva Dias IC, Carabelli B, Ishii DK, de Morais H, de Carvalho MC, Rizzo de Souza LE, Zanata SM, Brandão ML, Cunha TM, Ferraz AC, Cunha JM, Zanoveli JM. Indoleamine-2,3-Dioxygenase/Kynurenine Pathway as a Potential Pharmacological Target to Treat Depression Associated with Diabetes. Mol Neurobiol. 2016 Dec;53(10):6997-7009.

David BA, Rezende RM, Antunes MM, Santos MM, Freitas Lopes MA, Diniz AB, Sousa Pereira RV, Marchesi SC, Alvarenga DM, Nakagaki BN, Araújo AM, Dos Reis DS, Rocha RM, Marques PE, Lee WY, Deniset J, Liew PX, Rubino S, Cox L, Pinho V, Cunha TM, Fernandes GR, Oliveira AG, Teixeira MM, Kubes P, Menezes GB. Combination of Mass Cytometry and Imaging Analysis Reveals Origin, Location, and Functional Repopulation of Liver Myeloid Cells in Mice. Gastroenterology. 2016 Dec;151(6):1176-1191.

Davoli-Ferreira M, Fonseca DM, Mota CM, Dias MS, Lima-Junior DS, da Silva MV, Quirino GF, Zamboni DS, Silva JS, Mineo TW. Nucleotide-binding oligomerization domain-containing protein 2 prompts potent inflammatory stimuli during Neospora caninum infection. Sci Rep. 2016 Jul 5;6:29289.

D’Cunha TM, Daoud E, Rizzo D, Bishop AB, Russo M, Mourra G, Hamel L, Sedki F, Shalev U. Augmentation of Heroin Seeking Following Chronic Food Restriction in the Rat: Differential Role for Dopamine Transmission in the Nucleus Accumbens Shell and Core. Neuropsychopharmacology. 2016 Dec 7.

de Assis AM, da Silva JS, Rech A, Longoni A, Nonose Y, Repond C, de Bittencourt Pasquali MA, Moreira JC, Souza DO, Pellerin L. Cerebral Ketone Body Oxidation Is Facilitated by a High Fat Diet Enriched with Advanced Glycation End Products in Normal and Diabetic Rats. Front Neurosci. 2016 Nov 8;10:509.

de Castro DT, Valente ML, da Silva CH, Watanabe E, Siqueira RL, Schiavon MA, Alves OL, Dos Reis AC. Evaluation of antibiofilm and mechanical properties of new nanocomposites based on acrylic resins and silver vanadate nanoparticles. Arch Oral Biol. 2016 Jul;67:46-53.

de Molon RS, Hsu C, Bezouglaia O, Dry SM, Pirih FQ, Soundia A, Cunha FQ, Cirelli JA, Aghaloo TL, Tetradis S. Rheumatoid Arthritis Exacerbates the Severity of Osteonecrosis of the Jaws (ONJ) in Mice. A Randomized, Prospective, Controlled Animal Study. J Bone Miner Res. 2016 Aug;31(8):1596-607.

de Oliveira LF, Romano MM, de Carvalho EE, Cabeza JM, Salgado HC, Fazan Júnior R, Costa RS, da Silva JS, Higuchi Mde L, Maciel BC, Cunha-Neto E, Marin-Neto JA, Simões MV. Histopathological Correlates of Global and Segmental Left Ventricular Systolic Dysfunction in Experimental Chronic Chagas Cardiomyopathy. J Am Heart Assoc. 2016 Jan 21;5(1).

de Oliveira LM, de Oliveira TS, da Costa RM, de Souza Gil E, Costa EA, Passaglia Rde C, Filgueira FP, Ghedini PC. The vasorelaxant effect of gallic acid involves endothelium-dependent and -independent mechanisms. Vascul Pharmacol. 2016 Jun;81:69-74.

de Paula Costa G, Lopes LR, da Silva MC, Horta AL, Pontes WM, Milanezi CM, Guedes PM, de Lima WG, Schulz R, da Silva JS, Talvani A. Doxycycline and Benznidazole Reduce the Profile of Th1, Th2, and Th17 Chemokines and Chemokine Receptors in Cardiac Tissue from Chronic Trypanosoma cruzi-Infected Dogs. Mediators Inflamm. 2016;2016:3694714.

de Souza Buriol VC, Hirakata V, Goldani MZ, da Silva CH. Temporal evolution of the risk factors associated with low birth weight rates in Brazilian capitals (1996-2011). Popul Health Metr. 2016 May 3;14:15.

Di Giovanni SE, Cunha TM, Duarte AL, Alves I. Endometrial Tuberculosis Simulating an Ovarian Cancer: a case report. Acta Med Port. 2016 Jun;29(6):412-415.

Diniz EM, Poiani JG, Taft CA, Silva CH. Structure-based drug design, molecular dynamics and ADME/Tox to investigate protein kinase anti-cancer agents. Current Bioactive Compounds, 2016.

Diniz EM, Tomich de Paula da Silva CH, Gómez-Perez V, Federico LB, Campos Rosa JM. GRIND2-based 3D-QSAR and prediction of activity spectra for symmetrical bis-pyridinium salts with promastigote antileishmanial activity. J Biomol Struct Dyn. 2016 Sep 6:1-11.

Dos Santos Picanço LC, Ozela PF, de Fátima de Brito Brito M, Pinheiro AA, Padilha EC, Braga FS, de Paula da Silva CH, Dos Santos CB, Rosa JM, da Silva Hage-Melim LI. Alzheimer’s disease: A review from the pathophysiology to diagnosis, new perspectives for pharmacological treatment. Curr Med Chem. 2016 Dec 12.

Ellebedy AH, Jackson KJ, Kissick HT, Nakaya HI, Davis CW, Roskin KM, McElroy AK, Oshansky CM, Elbein R, Thomas S, Lyon GM, Spiropoulou CF, Mehta AK, Thomas PG, Boyd SD, Ahmed R. Defining antigen-specific plasmablast and memory B cell subsets in human blood after viral infection or vaccination. Nat Immunol. 2016 Oct;17(10):1226-34.

Fattori V, Pinho-Ribeiro FA, Borghi SM, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA Jr. Curcumin inhibits superoxide anion-induced pain-like behavior and leukocyte recruitment by increasing Nrf2 expression and reducing NF-κB activation. Inflamm Res. 2015 Dec;64(12):993-1003.

Fattori V, Serafim KG, Zarpelon AC, Borghi SM, Pinho-Ribeiro FA, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA Jr. Differential regulation of oxidative stress and cytokine production by endothelin ET(A) and ET(B) receptors in superoxide anion-induced inflammation and pain in mice. J Drug Target. 2016 Oct 5:1-27.

Federico LB, Almeida JR, Taft CA, Silva CH. Ligand and Structure-Based Drug Design as Strategies for the Screening of New BACE1 Inhibitor Candidates. Current Physical Chemistry, 2016.

Federico LB, Santos CB, Lobato CC, Gomes JS, Rosa JC, Silva CH. Ligand- and structure-based drug design of novel calcium channel blockers. Journal of Computational and Theoretical Nanoscience, 2016.

Fernandes TD, Cunha LD, Ribeiro JM, Massis LM, Lima-Junior DS, Newton HJ, Zamboni DS. Murine Alveolar Macrophages Are Highly Susceptible to Replication of Coxiella burnetii Phase II In Vitro. Infect Immun. 2016 Aug 19;84(9):2439-48.

Ferreira CR, de Souza DF, Cunha TM, Tavares M, Reis SS, Pedroso RS, Röder DV. The effectiveness of a bundle in the prevention of ventilator-associated pneumonia. Braz J Infect Dis. 2016 May-Jun;20(3):267-71.

Ferreira LR, Ferreira FM, Nakaya HI, Deng X, Cândido DD, de Oliveira LC, Billaud JN, Lanteri MC, Rigaud VO, Seielstad M, Kalil J, Fernandes F, Ribeiro AL, Sabino EC, Cunha-Neto E. Blood Gene Signatures of Chagas disease Cardiomyopathy with or without ventricular dysfunction. J Infect Dis. 2016 Dec 21.

Figueredo AS, Oliveira MG, Safadi GM, Silva CH, Silva VB, Aquino GL. The Natural Alkaloid Piperine and its Acid and Ester Synthetic Derivatives are Acetylcholinesterase Inhibitors. Current Physical Chemistry, 2016.

Forstner R, Meissnitzer M, Cunha TM. Update on Imaging of Ovarian Cancer. Curr Radiol Rep. 2016;4:31.

Forstner R, Thomassin-Naggara I, Cunha TM, Kinkel K, Masselli G, Kubik-Huch R, Spencer JA, Rockall A. ESUR recommendations for MR imaging of the sonographically indeterminate adnexal mass: an update. Eur Radiol. 2016 Oct 21.

Forstner R, Thomassin-Naggara I, Cunha TM, Kinkel K, Masselli G, Kubik-Huch R, Spencer JA, Rockall A. Erratum to: ESUR recommendations for MR imaging of the sonographically indeterminate adnexal mass: an update. Eur Radiol. 2016 Dec 5.

Franca RF, Costa RS, Silva JR, Peres RS, Mendonça LR, Colón DF, Alves-Filho JC, Cunha FQ. IL-33 signaling is essential to attenuate viral-induced encephalitis development by downregulating iNOS expression in the central nervous system. J Neuroinflammation. 2016 Jun 22;13(1):159.

Franchin M, Cólon DF, Castanheira FV, da Cunha MG, Bueno-Silva B, Alencar SM, Cunha TM, Rosalen PL. Vestitol Isolated from Brazilian Red Propolis Inhibits Neutrophils Migration in the Inflammatory Process: Elucidation of the Mechanism of Action. J Nat Prod. 2016 Apr 22;79(4):954-60.

Franchin M, Colón DF, da Cunha MG, Castanheira FV, Saraiva AL, Bueno-Silva B, Alencar SM, Cunha TM, Rosalen PL. Neovestitol, an isoflavonoid isolated from Brazilian red propolis, reduces acute and chronic inflammation: involvement of nitric oxide and IL-6. Sci Rep. 2016 Nov 7;6:36401.

Franchin M, Rosalen PL, da Cunha MG, Silva RL, Colón DF, Bassi GS, de Alencar SM, Ikegaki M, Alves-Filho JC, Cunha FQ, Beutler JA, Cunha TM. Cinnamoyloxy-mammeisin Isolated from Geopropolis Attenuates Inflammatory Process by Inhibiting Cytokine Production: Involvement of MAPK, AP-1, and NF-κB. J Nat Prod. 2016 Jul 22;79(7):1828-33.

Galvão I, Dias AC, Tavares LD, Rodrigues IP, Queiroz-Junior CM, Costa VV, Reis AC, Ribeiro Oliveira RD, Louzada-Junior P, Souza DG, Leng L, Bucala R, Sousa LP, Bozza MT, Teixeira MM, Amaral FA. Macrophage migration inhibitory factor drives neutrophil accumulation by facilitating IL-1β production in a murine model of acute gout. J Leukoc Biol. 2016 Jun;99(6):1035-43.

Geraldo MV, Nakaya HI, Kimura ET. Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer. Oncotarget. 2016 Dec 24.

Gohar EY, Giachini FR, Pollock DM, Tostes RC. Role of the endothelin system in sexual dimorphism in cardiovascular and renal diseases. Life Sci. 2016 Aug 15;159:20-9.

Gonzaga NA, Simplicio JA, Leite LN, Vale GT, Carballido JM, Alves-Filho JC, Tirapelli CR. Data on the mechanisms underlying succinate-induced aortic contraction. Data Brief. 2016 Aug 31;9:206-12.

Guerrero AT, Pinto LG, Cunha FQ, Ferreira SH, Alves-Filho JC, Verri WA Jr, Cunha TM. Mechanisms underlying the hyperalgesic responses triggered by joint activation of TLR4. Pharmacol Rep. 2016 Dec;68(6):1293-1300.

Huang L, Ou R, Rabelo de Souza G, Cunha TM, Lemos H, Mohamed E, Li L, Pacholczyk G, Randall J, Munn DH, Mellor AL. Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase. PLoS Pathog. 2016 May 11;12(5):e1005615.

Im SJ, Hashimoto M, Gerner MY, Lee J, Kissick HT, Burger MC, Shan Q, Hale JS, Lee J, Nasti TH, Sharpe AH, Freeman GJ, Germain RN, Nakaya HI, Xue HH, Ahmed R. Defining CD8(+) T cells that provide the proliferative burst after PD-1 therapy. Nature. 2016 Sep 15;537(7620):417-421.

Kanashiro A, Sônego F, Ferreira RG, Castanheira FV, Leite CA, Borges VF, Nascimento DC, Cólon DF, Alves-Filho JC, Ulloa L, Cunha FQ. Therapeutic potential and limitations of cholinergic anti-inflammatory pathway in sepsis. Pharmacol Res. 2016 Dec 12;117:1-8.

Kanashiro A, Talbot J, Peres RS, Pinto LG, Bassi GS, Cunha TM, Cunha FQ. Neutrophil Recruitment and Articular Hyperalgesia in Antigen-Induced Arthritis are Modulated by the Cholinergic Anti-Inflammatory Pathway. Basic Clin Pharmacol Toxicol. 2016 Nov;119(5):453-457.

Kasturi SP, Kozlowski PA, Nakaya HI, Burger MC, Russo P, Pham M, Kovalenkov Y, Silveira EL, Havenar-Daughton C, Burton SL, Kilgore KM, Johnson MJ, Nabi R, Legere T, Sher ZJ, Chen X, Amara RR, Hunter E, Bosinger SE, Spearman P, Crotty S, Villinger F, Derdeyn CA, Wrammert J, Pulendran B. Adjuvanting an SIV vaccine with TLR ligands encapsulated in nanoparticles induces persistent antibody responses and enhanced protection in TRIM5α restrictive macaques. J Virol. 2016 Dec 7.

Kawano DF, Silva CH, Taft CA. Design of a New Synthetically Accessible Antibacterial Sulfona-mide Through Quantitative Structure-Activity Relationship (QSAR) Studies. Current Physical Chemistry, 2016.

Kawano DF, Taft CA, Silva CH. Prospecting for new inhibitors of anaplastic lymphoma kinase, a clinically relevant oncogenic drug target. Current Bioactive Compounds, 2016.

Leite LN, Gonzaga NA, Simplicio JA, do Vale GT, Carballido JM, Alves-Filho JC, Tirapelli CR. Pharmacological characterization of the mechanisms underlying the vascular effects of succinate. Eur J Pharmacol. 2016 Oct 15;789:334-43.

Lever M, Silveira EL, Nakaya HI. Systems Vaccinology Applied to DNA Vaccines: Perspective and Challenges. Curr Issues Mol Biol. 2016 Sep 20;22:1-16.

Lima VV, Giachini FR, Matsumoto T, Li W, Bressan AF, Chawla D, Webb RC, Ergul A, Tostes RC. High-fat diet increases O-GlcNAc levels in cerebral arteries: a link to vascular dysfunction associated with hyperlipidaemia/obesity? Clin Sci (Lond). 2016 Jun 1;130(11):871-80.

Lima VV, Zemse SM, Chiao CW, Bomfim GF, Tostes RC, Clinton Webb R, Giachini FR. Interleukin-10 limits increased blood pressure and vascular RhoA/Rho-kinase signaling in angiotensin II-infused mice. Life Sci. 2016 Jan 15;145:137-43.

Longhi-Balbinot DT, Rossaneis AC, Pinho-Ribeiro FA, Bertozzi MM, Cunha FQ, Alves-Filho JC, Cunha TM, Peron JP, Miranda KM, Casagrande R, Verri WA Jr. The nitroxyl donor, Angeli’s salt, reduces chronic constriction injury-induced neuropathic pain. Chem Biol Interact. 2016 Aug 25;256:1-8.

Longoni A, Kolling J, dos Santos TM, dos Santos JP, da Silva JS, Pettenuzzo L, Gonçalves CA, de Assis AM, Quincozes-Santos A, Wyse AT. 1,25-Dihydroxyvitamin D3 exerts neuroprotective effects in an ex vivo model of mild hyperhomocysteinemia. Int J Dev Neurosci. 2016 Feb;48:71-9.

Lopes AH, Brandolini L, Aramini A, Bianchini G, Silva RL, Zaperlon AC, Verri WA Jr, Alves-Filho JC, Cunha FQ, Teixeira MM, Allegretti M, Cunha TM. DF2755A, a novel non-competitive allosteric inhibitor of CXCR1/2, reduces inflammatory and post-operative pain. Pharmacol Res. 2016 Jan;103:69-79.

Luz AB, da Silva CH, Nascimento MV, de Campos Facchin BM, Baratto B, Fröde TS, Reginatto FH, Dalmarco EM. The anti-inflammatory effect of Ilex paraguariensis A. St. Hil (Mate) in a murine model of pleurisy. Int Immunopharmacol. 2016 Jul;36:165-72.

Martelli-Palomino G, Paoliello-Paschoalato AB, Crispim JC, Rassi DM, Oliveira RD, Louzada P, Lucisano-Valim YM, Donadi EA. DNA damage increase in peripheral neutrophils from patients with rheumatoid arthritis is associated with the disease activity and the presence of shared epitope. Clin Exp Rheumatol. 2016 Nov 14.

Mascarenhas DP, Zamboni DS. Inflammasome biology taught by Legionella pneumophila. J Leukoc Biol. 2016 Dec 20.

Massis LM, Assis-Marques MA, Castanheira FV, Capobianco YJ, Balestra AC, Escoll P, Wood RE, Manin GZ, Correa VM, Alves-Filho JC, Cunha FQ, Buchrieser C, Borges MC, Newton HJ, Zamboni DS. Legionella longbeachae is immunologically silent and highly virulent in vivo. J Infect Dis. 2016 Dec 8.

Milbradt BG, da Silva JS, Silveira AS, Dutra LO, Pereira RD, Callegaro MD, Emanuelli T. Eggshell fractions containing different particle sized affect mineral absorption but not bone mineral retention in growing rats. Int J Food Sci Nutr. 2016 Sep 7:1-9.

Moreira JD, Pernomian L, Gomes MS, Moreira RP, do Prado AF, da Silva CH, de Oliveira AM. Enhanced nitric oxide generation from nitric oxide synthases as the cause of increased peroxynitrite formation during acute restraint stress: Effects on carotid responsiveness to angiotensinergic stimuli in type-1 diabetic rats. Eur J Pharmacol. 2016 Jul 15;783:11-22.

Mota JM, Leite CA, Souza LE, Melo PH, Nascimento DC, de-Deus-Wagatsuma VM, Temporal J, Figueiredo F, Noushmehr H, Alves-Filho JC, Cunha FQ, Rego EM. Post-Sepsis State Induces Tumor-Associated Macrophage Accumulation through CXCR4/CXCL12 and Favors Tumor Progression in Mice. Cancer Immunol Res. 2016 Apr;4(4):312-22.

Moura MR, Araújo CG, Prado MM, Paro HB, Pinto RM, Abdallah VO, Mendonça TM, Silva CH. Factors associated with the quality of life of mothers of preterm infants with very low birth weight: a 3-year follow-up study. Qu [al Life Res. 2016 Nov 25.

Muñoz M, Craske M, Severino P, de Lima TM, Labhart P, Chammas R, Velasco IT, Machado MC, Egan B, Nakaya HI, Pinheiro da Silva F. Antimicrobial peptide LL-37 participates in the transcriptional regulation of melanoma cells. J Cancer. 2016 Nov 26;7(15):2341-2345.

Nakaya HI, Clutterbuck E, Kazmin D, Wang L, Cortese M, Bosinger SE, Patel NB, Zak DE, Aderem A, Dong T, Del Giudice G, Rappuoli R, Cerundolo V, Pollard AJ, Pulendran B, Siegrist CA. Systems biology of immunity to MF59-adjuvanted versus nonadjuvanted trivalent seasonal influenza vaccines in early childhood. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1853-8.

Nakiri GS, Monsignore LM, de Siqueira FM, Louzada P Jr, Castro-Afonso LH, Abud DG. Transhepatic Embolization of Bilateral Pulmonary Artery Aneurysm with N-Butyl Cyanoacrylate and Coils in Behçet Disease. J Vasc Interv Radiol. 2016 Feb;27(2):293-5.

Nascimento MM, Melo TR, Pinto RM, Morales NM, Mendonça TM, Paro HB, Silva CH. Parents’ perception of health-related quality of life in children and adolescents with excess weight. J Pediatr (Rio J). 2016 Jan-Feb;92(1):65-72.

Nascimento MS, Ferreira MD, Quirino GF, Maruyama SR, Krishnaswamy JK, Liu D, Berlink J, Fonseca DM, Zamboni DS, Carregaro V, Almeida RP, Cunha TM, Eisenbarth SS, Silva JS. NOD2-RIP2-Mediated Signaling Helps Shape Adaptive Immunity in Visceral Leishmaniasis. J Infect Dis. 2016 Dec 1;214(11):1647-1657.

Nonato AO, Olivon VC, Dela Justina V, Zanotto CZ, Webb RC, Tostes RC, Lima VV, Giachini FR. Impaired Ca(2+) Homeostasis and Decreased Orai1 Expression Modulates Arterial Hyporeactivity to Vasoconstrictors During Endotoxemia. Inflammation. 2016 Jun;39(3):1188-97.

Okada SS, de Oliveira EM, de Araújo TH, Rodrigues MR, Albuquerque RC, Mortara RA, Taniwaki NN, Nakaya HI, Campa A, Moreno AC. Myeloperoxidase in human peripheral blood lymphocytes: Production and subcellular localization. Cell Immunol. 2016 Feb;300:18-25.

Palmeiro MM, Cunha TM, Loureiro AL, Esteves G. A rare benign ovarian tumour. BMJ Case Rep. 2016 Mar 1;2016.

Penha Filho RA, Diaz SJ, Medina Tda S, Chang YF, da Silva JS, Berchieri A Jr. Evaluation of protective immune response against fowl typhoid in chickens vaccinated with the attenuated strain Salmonella Gallinarum ΔcobSΔcbiA. Res Vet Sci. 2016 Aug;107:220-7.

Peracini A, Regis RR, Souza RF, Pagnano VO, Silva CH, Paranhos HF. Alkaline Peroxides Versus Sodium Hypochlorite for Removing Denture Biofilm: a Crossover Randomized Trial. Braz Dent J. 2016 Oct-Dec;27(6):700-704.

Peres RS, Menezes GB, Teixeira MM, Cunha FQ. Pharmacological opportunities to control inflammatory diseases through inhibition of the leukocyte recruitment. Pharmacol Res. 2016 Oct;112:37-48.

Picanço LC, Bittencourt JA, Henriques SV, da Silva JS, Oliveira JM, Ribeiro JR, Sanjay AB, Carvalho JC, Stien D, Silva JO. Pharmacological activity of Costus spicatus in experimental Bothrops atrox envenomation. Pharm Biol. 2016 Oct;54(10):2103-10.

Picanco LC, Ozela P, Brito MF, Pinheiro A, Padilha E, Braga F, Silva CH, Santos CB, Campos JM, Hage-Melim LI. Alzheimer’s disease: A review from the pathophysiology to diagnosis, new perspectives for pharmacological treatment. Current Medicinal Chemistry, 2016.

Pinho-Ribeiro FA, Fattori V, Zarpelon AC, Borghi SM, Staurengo-Ferrari L, Carvalho TT, Alves-Filho JC, Cunha FQ, Cunha TM, Casagrande R, Verri WA Jr. Pyrrolidine dithiocarbamate inhibits superoxide anion-induced pain and inflammation in the paw skin and spinal cord by targeting NF-κB and oxidative stress. Inflammopharmacology. 2016 Jun;24(2-3):97-107.

Pinho-Ribeiro FA, Zarpelon AC, Mizokami SS, Borghi SM, Bordignon J, Silva RL, Cunha TM, Alves-Filho JC, Cunha FQ, Casagrande R, Verri WA Jr. The citrus flavonone naringenin reduces lipopolysaccharide-induced inflammatory pain and leukocyte recruitment by inhibiting NF-κB activation. J Nutr Biochem. 2016 Jul;33:8-14.

Pinke KH, Lima HG, Cunha FQ, Lara VS. Mast cells phagocyte Candida albicans and produce nitric oxide by mechanisms involving TLR2 and Dectin-1. Immunobiology. 2016 Feb;221(2):220-7.

Pucca MB, Cerni FA, Cordeiro FA, Peigneur S, Cunha TM, Tytgat J, Arantes EC. Ts8 scorpion toxin inhibits the Kv4.2 channel and produces nociception in vivo. Toxicon. 2016 Sep 1;119:244-52.

Quadros AU, Cunha TM. C5a and pain development: An old molecule, a new target. Pharmacol Res. 2016 Oct;112:58-67.

Quadros AU, Pinto LG, Fonseca MM, Kusuda R, Cunha FQ, Cunha TM. Dynamic weight bearing is an efficient and predictable method for evaluation of arthritic nociception and its pathophysiological mechanisms in mice. Sci Rep. 2015 Oct 29;5:14648.

Ramos-Junior ES, Leite GA, Carmo-Silva CC, Taira TM, Neves KB, Colón DF, da Silva LA, Salvador SL, Tostes RC, Cunha FQ, Fukada SY. Adipokine Chemerin Bridges Metabolic Dyslipidemia and Alveolar Bone Loss in Mice. J Bone Miner Res. 2016 Dec 28.

Ravindran R, Loebbermann J, Nakaya HI, Khan N, Ma H, Gama L, Machiah DK, Lawson B, Hakimpour P, Wang YC, Li S, Sharma P, Kaufman RJ, Martinez J, Pulendran B. The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation. Nature. 2016 Mar 24;531(7595):523-7.

Ribeiro RA, Wanderley CW, Wong DV, Mota JM, Leite CA, Souza MH, Cunha FQ, Lima-Júnior RC. Irinotecan- and 5-fluorouracil-induced intestinal mucositis: insights into pathogenesis and therapeutic perspectives. Cancer Chemother Pharmacol. 2016 Nov;78(5):881-893.

Rodrigues FL, Lopes RA, Fais RS, de Oliveira L, Prado CM, Tostes RC, Carneiro FS. Erectile dysfunction in heart failure rats is associated with increased neurogenic contractions in cavernous tissue and internal pudendal artery. Life Sci. 2016 Jan 15;145:9-18.

Santa-Cecília FV, Socias B, Ouidja MO, Sepulveda-Diaz JE, Acuña L, Silva RL, Michel PP, Del-Bel E, Cunha TM, Raisman-Vozari R. Doxycycline Suppresses Microglial Activation by Inhibiting the p38 MAPK and NF-kB Signaling Pathways. Neurotox Res. 2016 May;29(4):447-59.

Sant’Anna MB, Kusuda R, Bozzo TA, Bassi GS, Alves-Filho JC, Cunha FQ, Ferreira SH, Souza GR, Cunha TM. Medial plantar nerve ligation as a novel model of neuropathic pain in mice: pharmacological and molecular characterization. Sci Rep. 2016 May 27;6:26955.

Santos CB, Silva CH, Serafim RB, Rodriguez D, Padilha E, Freitas C. New PPARα/γ/δ Optimal Activator Rationally Designed by Computational Methods. Journal of the Brazilian Chemical Society (Impresso), 2016.

Santos CF, Silva ES, Martins AM, Silva CH, Santos CB, Hage-Melim LI. Molecular Modeling of Peptide Derivatives NS3 Protease Inhibitors of the Type 2 Dengue Virus. Current Physical Chemistry, 2016.

Santos SS, Carmo AM, Brunialti MK, Machado FR, Azevedo LC, Assunção M, Trevelin SC, Cunha FQ, Salomao R. Modulation of monocytes in septic patients: preserved phagocytic activity, increased ROS and NO generation, and decreased production of inflammatory cytokines. Intensive Care Med Exp. 2016 Dec;4(1):5.

Schons-Fonseca L, da Silva JB, Milanez JS, Domingos RH, Smith JL, Nakaya HI, Grossman AD, Ho PL, da Costa RM. Analysis of LexA binding sites and transcriptomics in response to genotoxic stress in Leptospira interrogans. Nucleic Acids Res. 2016 Feb 18;44(3):1179-91.

Schroder WA, Anraku I, Le TT, Hirata TD, Nakaya HI, Major L, Ellis JJ, Suhrbier A. SerpinB2 Deficiency Results in a Stratum Corneum Defect and Increased Sensitivity to Topically Applied Inflammatory Agents. Am J Pathol. 2016 Jun;186(6):1511-23.

Scotton DC, Azevedo MD, Sestari I, Da Silva JS, Souza LA, Peres LE, Leal GA Jr, Figueira A. Expression of the Theobroma cacao Bax-inhibitor-1 gene in tomato reduces infection by the hemibiotrophic pathogen Moniliophthora perniciosa. Mol Plant Pathol. 2016 Jul 25.

Serafim KG, Navarro SA, Zarpelon AC, Pinho-Ribeiro FA, Fattori V, Cunha TM, Alves-Filho JC, Cunha FQ, Casagrande R, Verri WA Jr. Bosentan, a mixed endothelin receptor antagonist, inhibits superoxide anion-induced pain and inflammation in mice. Naunyn Schmiedebergs Arch Pharmacol. 2015 Nov;388(11):1211-21.

Silva DF, Alves CQ, Brandão HN, David JM, David JP, Silva RL, Franchin M, Cunha TM, Martins FT, Oliveira CM. Poligalen, a new coumarin from Polygala boliviensis, reduces the release of TNF and IL-6 independent of NF-kB downregulation. Fitoterapia. 2016 Sep;113:139-43.

Silva IX, Oliveira MG, Conceição EC, Taft CA, Silva CH, Silva VB. Binding model of capsaicin is able to reach the peripheral anionic site of acetylcholinesterase. Current Bioactive Compounds, 2016.

Silva RL, Castanheira FV, Figueiredo JG, Bassi GS, Ferreira SH, Cunha FQ, Cunha TM, Kanashiro A. Pharmacological Beta-Adrenergic Receptor Activation Attenuates Neutrophil Recruitment by a Mechanism Dependent on Nicotinic Receptor and the Spleen. Inflammation. 2016 Aug;39(4):1405-13.

Simplicio JA, do Vale GT, Gonzaga NA, Leite LN, Hipólito UV, Pereira CA, Tostes RC, Tirapelli CR. Reactive oxygen species derived from NAD(P)H oxidase play a role on ethanol-induced hypertension and endothelial dysfunction in rat resistance arteries. J Physiol Biochem. 2016 Oct 8.

Simplicio JA, Hipólito UV, Vale GT, Callera GE, Pereira CA, Touyz RM, Tostes RC, Tirapelli CR. Acute Ethanol Intake Induces NAD(P)H Oxidase Activation and Rhoa Translocation in Resistance Arteries. Arq Bras Cardiol. 2016 Nov;107(5):427-436.

Sônego F, Castanheira FV, Ferreira RG, Kanashiro A, Leite CA, Nascimento DC, Colón DF, Borges Vde F, Alves-Filho JC, Cunha FQ. Paradoxical Roles of the Neutrophil in Sepsis: Protective and Deleterious. Front Immunol. 2016 Apr 26;7:155.

Souza JA, Medeiros MC, Rocha FR, de Aquino SG, Ávila-Campos MJ, Spolidorio LC, Zamboni DS, Graves DT, Rossa C Junior. Role of NOD2 and RIP2 in host-microbe interactions with Gram-negative bacteria: insights from the periodontal disease model. Innate Immun. 2016 Nov;22(8):598-611.

Souza LR, Picanco RM, Pinheiro AA, Silva KR, Silva CH, Santos CB, Hage-Melim, LI. Development of Monoamine Oxidase B Inhibitors with Antiparkinson Activity. Current Physical Chemistry, 2016.

Souza-Oliveira AC, Cunha TM, Passos LB, Lopes GC, Gomes FA, Röder DV. Ventilator-associated pneumonia: the influence of bacterial resistance, prescription errors, and de-escalation of antimicrobial therapy on mortality rates. Braz J Infect Dis. 2016 Sep-Oct;20(5):437-43.

Toffoli Ribeiro C, Louzada Júnior P, de Sá MF. Correlation between Systemic Lupus Erythematosus Activity and Plasma Levels of Monomeric Prolactin and Macroprolactin. Endocr Metab Immune Disord Drug Targets. 2016;16(1):21-7.

Tostes RC, Carneiro FS, Carvalho MH, Reckelhoff JF. Reactive oxygen species: players in the cardiovascular effects of testosterone. Am J Physiol Regul Integr Comp Physiol. 2016 Jan 1;310(1):R1-14.

Trevelin SC, Carlos D, Beretta M, da Silva JS, Cunha FQ. Diabetes Mellitus and Sepsis: A Challenging Association. Shock. 2016 Oct 26.

Trevelin SC, Dos Santos CX, Ferreira RG, de Sá Lima L, Silva RL, Scavone C, Curi R, Alves-Filho JC, Cunha TM, Roxo-Júnior P, Cervi MC, Laurindo FR, Hothersall JS, Cobb AM, Zhang M, Ivetic A, Shah AM, Lopes LR, Cunha FQ. Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state. Sci Rep. 2016 Oct 4;6:34581.

Turato WM, Sales-Campos H, Braga CB, Cunha SF, Silvah JH, da Silva JS, Marchini JS, de Barros Cardoso CR. The impact of intestinal resection on the immune function of short bowel syndrome patients. Hum Immunol. 2016 Dec;77(12):1202-1208.

Veras FP, Peres RS, Saraiva AL, Pinto LG, Louzada-Junior P, Cunha TM, Paschoal JA, Cunha FQ, Alves-Filho JC. Fructose 1,6-bisphosphate, a high-energy intermediate of glycolysis, attenuates experimental arthritis by activating anti-inflammatory adenosinergic pathway. Sci Rep. 2015 Oct 19;5:15171.

Vilela FM, Oliveira FM, Vicentini FT, Casagrande R, Verri WA Jr, Cunha TM, Fonseca MJ. Commercial sunscreen formulations: UVB irradiation stability and effect on UVB irradiation-induced skin oxidative stress and inflammation. J Photochem Photobiol B. 2016 Oct;163:413-20.

Winck AD, Heinzmann-Filho JP, Soares RB, da Silva JS, Woszezenki CT, Zanatta LB. Effects of obesity on lung volume and capacity in children and adolescents: a systematic review. Rev Paul Pediatr. 2016 Dec;34(4):510-517.

Zapata-Sudo G, da Costa Nunes IK, Araujo JS, da Silva JS, Trachez MM, da Silva TF, da Costa FP, Sudo RT, Barreiro EJ, Lima LM. Synthesis, solubility, plasma stability, and pharmacological evaluation of novel sulfonylhydrazones designed as anti-diabetic agents. Drug Des Devel Ther. 2016 Sep 9;10:2869-2879.

Zarpelon AC, Rodrigues FC, Lopes AH, Souza GR, Carvalho TT, Pinto LG, Xu D, Ferreira SH, Alves-Filho JC, McInnes IB, Ryffel B, Quesniaux VF, Reverchon F, Mortaud S, Menuet A, Liew FY, Cunha FQ, Cunha TM, Verri WA Jr. Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain. FASEB J. 2016 Jan;30(1):54-65.

Zoccal KF, Sorgi CA, Hori JI, Paula-Silva FW, Arantes EC, Serezani CH, Zamboni DS, Faccioli LH. Opposing roles of LTB4 and PGE2 in regulating the inflammasome-dependent scorpion venom-induced mortality. Nat Commun. 2016 Feb 23;7:10760.