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Amaral JH, Rizzi ES, Alves-Lopes R, Pinheiro LC, Tostes RC, Tanus-Santos JE. Antioxidant and antihypertensive responses to oral nitrite involves activation of the Nrf2 pathway. Free Radic Biol Med. 2019 Sep;141:261-268. doi: 10.1016/j.freeradbiomed.2019.06.028. Epub 2019 Jun 25. PubMed PMID: 31251976.

Amarilla AA, Santos-Junior NN, Figueiredo ML, Luiz JPM, Fumagalli MJ, Colón DF, Lippi V, Alfonso HL, Lima-Junior DS, Trabuco AC, Spinieli RL, Desidera AC, Leite-Panissi CRA, Lauretti F, Mendoza SES, Silva CLA, Rego EM, Galvao-Lima LJ, Bassi GS, Penharvel Martíns SLB, Manrique WG, Alves-Filho JC, Cunha FQ, Peng NYG, Modhiran N, Setoh YX, Khromykh AA, Figueiredo LTM, Aquino VH. CCR2 Plays a Protective Role in Rocio Virus-Induced Encephalitis by Promoting Macrophage Infiltration Into the Brain. J Infect Dis. 2019 May 24;219(12):2015-2025.

Batista NV, Barbagallo M, Oliveira VLS, Castro-Gomes T, Oliveira RDR, Louzada-Junior P, Pinheiro GRC, Mantovani A, Teixeira MM, Garlanda C, Amaral FA. The Long Pentraxin 3 Contributes to Joint Inflammation in Gout by Facilitating the Phagocytosis of Monosodium Urate Crystals. J Immunol. 2019 Mar 15;202(6):1807-1814.

Benevides L, Costa RS, Tavares LA, Russo M, Martins GA, da Silva LLP, Arruda LK, Cunha FQ, Carregaro V, Silva JS. B lymphocyte-induced maturation protein 1 controls T(H)9 cell development, IL-9 production, and allergic inflammation. J Allergy Clin Immunol. 2019 Mar;143(3):1119-1130.e3.

Borghi SM, Fattori V, Pinho-Ribeiro FA, Domiciano TP, Miranda-Sapla MM, Zaninelli TH, Casagrande R, Pinge-Filho P, Pavanelli WR, Alves-Filho JC, Cunha FQ, Cunha TM, Verri WA Jr. Contribution of spinal cord glial cells to L. amazonensis experimental infection-induced pain in BALB/c mice. J Neuroinflammation. 2019 May 28;16(1):113.

Bressan AF, Fonseca GA, Tostes RC, Webb RC, Lima VV, Giachini FR. Interleukin-10 negatively modulates extracellular signal-regulated kinases 1 and 2 in aorta from hypertensive mouse induced by angiotensin II infusion. Fundam Clin Pharmacol. 2019 Feb;33(1):31-40.

Bruder-Nascimento T, Callera GE, Montezano AC, Belin de Chantemele EJ, Tostes RC, Touyz RM. Atorvastatin inhibits pro-inflammatory actions of aldosterone in vascular smooth muscle cells by reducing oxidative stress. Life Sci. 2019 Feb 2. pii: S0024-3205(19)30056-6.

Cardozo LE, Russo PST, Gomes-Correia B, Araujo-Pereira M, Sepúlveda-Hermosilla G, Maracaja-Coutinho V, Nakaya HI. webCEMiTool: Co-expression Modular Analysis Made Easy. Front Genet. 2019 Mar 6;10:146.

Colón DF, Wanderley CW, Franchin M, Silva CM, Hiroki CH, Castanheira FVS, Donate PB, Lopes AH, Volpon LC, Kavaguti SK, Borges VF, Speck-Hernandez CA, Ramalho F, Carlotti AP, Carmona F, Alves-Filho JC, Liew FY, Cunha FQ. Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis. Crit Care. 2019 Apr 8;23(1):113.

Corsi-Zuelli F, Fachim HA, Loureiro CM, Shuhama R, Bertozi G, Joca SRL, Menezes PR, Louzada-Junior P, Del-Ben CM. Prolonged Periods of Social Isolation From Weaning Reduce the Anti-inflammatory Cytokine IL-10 in Blood and Brain. Front Neurosci. 2019 Jan 11;12:1011.

Corrêa JD, Fernandes GR, Calderaro DC, Mendonça SMS, Silva JM, Albiero ML, Cunha FQ, Xiao E, Ferreira GA, Teixeira AL, Mukherjee C, Leys EJ, Silva TA, Graves DT. Oral microbial dysbiosis linked to worsened periodontal condition in rheumatoid arthritis patients. Sci Rep. 2019 Jun 10;9(1):8379.

Cunha JE, Barbosa GM, Castro PATS, Luiz BLF, Silva ACA, Russo TL, Vasilceac FA, Cunha TM, Cunha FQ, Salvini TF. Knee osteoarthritis induces atrophy and neuromuscular junction remodeling in the quadriceps and tibialis anterior muscles of rats. Sci Rep. 2019 Apr 24;9(1):6366.

da Costa RM, Rodrigues D, Pereira CA, Silva JF, Alves JV, Lobato NS, Tostes RC. Nrf2 as a Potential Mediator of Cardiovascular Risk in Metabolic Diseases. Front Pharmacol. 2019 Apr 12;10:382.

de Carvalho RVH, Andrade WA, Lima-Junior DS, Dilucca M, de Oliveira CV, Wang K, Nogueira PM, Rugani JN, Soares RP, Beverley SM, Shao F, Zamboni DS. Leishmania Lipophosphoglycan Triggers Caspase-11 and the Non-canonical Activation of the NLRP3 Inflammasome. Cell Rep. 2019 Jan 8;26(2):429-437.e5.

de Carvalho RVH, Silva ALN, Santos LL, Andrade WA, de Sá KSG, Zamboni DS. Macrophage priming is dispensable for NLRP3 inflammasome activation and restriction of Leishmania amazonensis replication. J Leukoc Biol. 2019 May 7.

de Lima DS, Cardozo LE, Maracaja-Coutinho V, Suhrbier A, Mane K, Jeffries D, Silveira ELV, Amaral PP, Rappuoli R, de Silva TI, Nakaya HI. Long noncoding RNAs are involved in multiple immunological pathways in response to vaccination. Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):17121-17126. doi: 10.1073/pnas.1822046116. Epub 2019 Aug 9. PubMed PMID: 31399544.

de Menezes MN, Salles ÉM, Vieira F, Amaral EP, Zuzarte-Luís V, Cassado A, Epiphanio S, Alvarez JM, Alves-Filho JC, Mota MM, D’Império-Lima MR. IL-1α promotes liver inflammation and necrosis during blood-stage Plasmodium chabaudi malaria. Sci Rep. 2019 May 20;9(1):7575.

Fachim HA, Loureiro CM, Corsi-Zuelli F, Shuhama R, Louzada-Junior P, Menezes PR, Dalton CF, Del-Ben CM, Reynolds GP. GRIN2B promoter methylation deficits in early-onset schizophrenia and its association with cognitive function. Epigenomics. 2019 Feb;11(4):401-410.

Fais RS, Rodrigues FL, Pereira CA, Mendes AC, Mestriner F, Tostes RC, Carneiro FS. The inflammasome NLRP3 plays a dual role on mouse corpora cavernosa relaxation. Sci Rep. 2019 Nov 7;9(1):16224.

Fonseca RC, Bassi GS, Brito CC, Rosa LB, David BA, Araújo AM, Nóbrega N, Diniz AB, Jesus ICG, Barcelos LS, Fontes MAP, Bonaventura D, Kanashiro A, Cunha TM, Guatimosim S, Cardoso VN, Fernandes SOA, Menezes GB, de Lartigue G, Oliveira AG. Vagus nerve regulates the phagocytic and secretory activity of resident macrophages in the liver. Brain Behav Immun. 2019 Oct;81:444-454. doi: 10.1016/j.bbi.2019.06.041. Epub 2019 Jul 2. PubMed PMID: 31271871.

Gomides APM, de Albuquerque CP, Santos ABV, Amorim RBC, Bértolo MB, Júnior PL, Santos IA, Giorgi RDN, Sacilotto NC, Radominski SC, Borghi FM, Guimarães MFBR, Pinto MRDC, Resende GG, Bonfiglioli KR, Silva HCD, Sauma MFLDC, Sauma ML, de Medeiros JB, Pereira IA, de Castro GRW, Brenol CV, Xavier RM, da Mota LMH, Pinheiro GDRC. Causes of synthetic disease-modifying drug discontinuation in rheumatoid arthritis: Data from a large real-life cohort. PLoS One. 2019 Mar 1;14(3):e0213219.

Gonçalves AV, Margolis SR, Quirino GFS, Mascarenhas DPA, Rauch I, Nichols RD, Ansaldo E, Fontana MF, Vance RE, Zamboni DS. Gasdermin-D and Caspase-7 are the key Caspase-1/8 substrates downstream of the NAIP5/NLRC4 inflammasome required for restriction of Legionella pneumophila. PLoS Pathog. 2019 Jun 28;15(6):e1007886.

Guimarães RM, Davoli-Ferreira M, Fonseca MM, Damasceno LEA, Santa-Cecilia FV, Kusuda R, Menezes GB, Cunha FQ, Alves-Filho JC, Cunha TM. Frontline Science: Blood-circulating leukocytes fail to infiltrate the spinal cord parenchyma after spared nerve injury. J Leukoc Biol. 2019 Sep;106(3):541-551.

Gupta G, Santana AKM, Gomes CM, Turatti A, Milanezi CM, Bueno Filho R, Fuzo C, Almeida RP, Carregaro V, Roselino AM, Silva JS. Inflammasome gene expression is associated with immunopathology in human localized cutaneous leishmaniasis. Cell Immunol. 2019 Jul;341:103920.

Lataro RM, Silva MAB, Mestriner FL, Cau SBA, Tostes RCA, Salgado HC. Chronic Treatment With Acetylcholinesterase Inhibitors Attenuates Vascular Dysfunction in Spontaneously Hypertensive Rats. Am J Hypertens. 2019 May 9;32(6):579-587.

Lourenco-Gonzalez Y, Fattori V, Domiciano TP, Rossaneis AC, Borghi SM, Zaninelli TH, Bernardy CCF, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA Jr. Repurposing of the Nootropic Drug Vinpocetine as an Analgesic and Anti-Inflammatory Agent: Evidence in a Mouse Model of Superoxide Anion-Triggered Inflammation. Mediators Inflamm. 2019 Mar 31;2019:6481812. doi:10.1155/2019/6481812. eCollection 2019. PubMed PMID: 31049025; PubMed Central PMCID: PMC6462340.

Maracaja-Coutinho V, Arias-Carrasco R, Nakaya HI, Aliaga-Tobar V. Predicting RNA Families in Nucleotide Sequences Using StructRNAfinder. Methods Mol Biol. 2019;1962:15-27. doi: 10.1007/978-1-4939-9173-0_2. PubMed PMID: 31020552.

Mascarenhas DPA, Zamboni DS. Inflammasome Activation in Legionella-Infected Macrophages. Methods Mol Biol. 2019;1921:305-319.

Meneghini AC, Koenigkam-Santos M, Pereira MC, Tonidandel PR, Terra-Filho J, Cunha FQ, Menezes MB, Vianna EO. Biomass smoke COPD has less tomographic abnormalities but worse hypoxemia compared with tobacco COPD. Braz J Med Biol Res. 2019;52(5):e8233.

Olatunji LA, Adeyanju OA, Michael OS, Usman TO, Tostes RC, Soladoye AO. Ameliorative effect of low-dose spironolactone on obesity and insulin resistance is through replenishment of estrogen in ovariectomized rats. Can J Physiol Pharmacol. 2019 Jan;97(1):65-74. doi: 10.1139/cjpp-2018-0416. Epub 2018 Nov 13. PubMed PMID: 30422674.

Pereira DMS, Teixeira SA, Murillo O, Peixoto EPM, Araújo MC, Sousa NCF, Monteiro-Neto V, Calixto JB, Cunha TM, Marinho CRF, Muscará MN, Fernandes ES. TRPV1 Contributes to Cerebral Malaria Severity and Mortality by Regulating Brain Inflammation. Oxid Med Cell Longev. 2019 May 16;2019:9451671.

Pérez MM, Martins LMS, Dias MS, Pereira CA, Leite JA, Gonçalves ECS, de Almeida PZ, de Freitas EN, Tostes RC, Ramos SG, de Zoete MR, Ryffel B, Silva JS, Carlos D. Interleukin-17/interleukin-17 receptor axis elicits intestinal neutrophil migration, restrains gut dysbiosis and lipopolysaccharide translocation in high-fat diet-induced metabolic syndrome model. Immunology. 2019 Apr;156(4):339-355.

Pinto LG, Souza GR, Kusuda R, Lopes AH, Sant’Anna MB, Cunha FQ, Ferreira SH, Cunha TM. Non-Peptidergic Nociceptive Neurons Are Essential for Mechanical Inflammatory Hypersensitivity in Mice. Mol Neurobiol. 2019 Aug;56(8):5715-5728.

Rossato MF, Hoffmeister C, Trevisan G, Bezerra F, Cunha TM, Ferreira J, Silva CR. Monosodium urate crystal interleukin-1β release is dependent on Toll-like receptor 4 and transient receptor potential V1 activation. Rheumatology (Oxford). 2019 Aug 23. pii: kez384. doi: 10.1093/rheumatology/kez384. [Epub ahead of print] PubMed PMID: 31504930.

Ryffel B, Alves-Filho JC. ILC2s and Basophils Team Up to Orchestrate IL-33-Induced Atopic Dermatitis. J Invest Dermatol. 2019 Oct;139(10):2077-2079.

Santa-Cecília FV, Ferreira DW, Guimaraes RM, Cecilio NT, Fonseca MM, Lopes AH, Davoli-Ferreira M, Kusuda R, Souza GR, Nachbur U, Alves-Filho JC, Teixeira MM, Zamboni DS, Cunha FQ, Cunha TM. The NOD2 signaling in peripheral macrophages contributes to neuropathic pain development. Pain. 2019 Jan;160(1):102-116.

Santos NBD, Franco RD, Camarini R, Munhoz CD, Eichler RAS, Gewehr MCF, Reckziegel P, Llanos RP, Dale CS, Silva VROD, Borges VF, Lima BHF, Cunha FQ, Visniauskas B, Chagas JR, Tufik S, Peres FF, Abilio VC, Florio JC, Iwai LK, Rioli V, Presoto BC, Guimaraes AO, Pesquero JB, Bader M, Castro LM, Ferro ES. Thimet Oligopeptidase (EC 3.4.24.15) Key Functions Suggested by Knockout Mice Phenotype Characterization. Biomolecules. 2019 Aug 19;9(8). pii: E382.

Schneider AH, Kanashiro A, Dutra SGV, Souza RDN, Veras FP, Cunha FQ, Ulloa L, Mecawi AS, Reis LC, Malvar DDC. Estradiol replacement therapy regulates innate immune response in ovariectomized arthritic mice. Int Immunopharmacol. 2019 Jul;72:504-510.

Schroder WA, Hirata TD, Le TT, Gardner J, Boyle GM, Ellis J, Nakayama E, Pathirana D, Nakaya HI, Suhrbier A. SerpinB2 inhibits migration and promotes a resolution phase signature in large peritoneal macrophages. Sci Rep. 2019 Aug 27;9(1):12421.

Siervo GEML, Ogo FM, Staurengo-Ferrari L, Anselmo-Franci JA, Cunha FQ, Cecchini R, Guarnier FA, Verri WA Jr, Fernandes GSA. Sleep restriction Turing peripuberty unbalances sexual hormones and testicular cytokines in rats. Biol 2019 Jan 1;100(1):112-122.

Silva RL, Silveira GT, Wanderlei CW, Cecilio NT, Maganin AGM, Franchin M, Marques LMM, Lopes NP, Crippa JA, Guimarães FS, Alves-Filho JCF, Cunha FQ, Cunha TM. DMH-CBD, a cannabidiol analog with reduced cytotoxicity, inhibits TNF production by targeting NF-kB activity dependent on A(2A) receptor. Toxicol Appl Pharmacol. 2019 Apr 1;368:63-71.

Soares-Schanoski A, Baptista Cruz N, de Castro-Jorge LA, de Carvalho RVH, Santos CAD, Rós ND, Oliveira Ú, Costa DD, Santos CLSD, Cunha MDP, Oliveira MLS, Alves JC, Océa RALC, Ribeiro DR, Gonçalves ANA, Gonzalez-Dias P, Suhrbier A, Zanotto PMA, Azevedo IJ, Zamboni DS, Almeida RP, Ho PL, Kalil J, Nishiyama MY Junior, Nakaya HI. Systems analysis of subjects acutely infected with the Chikungunya virus. PLoS Pathog. 2019 Jun 18;15(6):e1007880.

Spiller F, Oliveira Formiga R, Fernandes da Silva Coimbra J, Alves-Filho JC, Cunha TM, Cunha FQ. Targeting nitric oxide as a key modulator of sepsis, arthritis and pain. Nitric Oxide. 2019 Aug 1;89:32-40.

Taira TM, Lima V, Prado DS, Silva TA, Issa JPM, da Silva LAB, Zamboni DS, Cunha FQ, Fukada SY. NLRP12 Attenuates Inflammatory Bone Loss in Experimental Apical Periodontitis. J Dent Res. 2019 Apr;98(4):476-484.

Wilches-Buitrago L, Viacava PR, Cunha FQ, Alves-Filho JC, Fukada SY. Fructose 1,6-bisphosphate inhibits osteoclastogenesis by attenuating RANKL-induced NF-κB/NFATc-1. Inflamm Res. 2019 May;68(5):415-421.

Wong DVT, Ribeiro-Filho HV, Wanderley CWS, Leite CAVG, Lima JB, Assef ANB, Cajado AG, Batista GLP, González RH, Silva KO, Borges LPC, Alencar NMN, Wilke DV, Cunha TM, Figueira ACM, Cunha FQ, Lima-Júnior RCP. SN-38, the active metabolite of irinotecan, inhibits the acute inflammatory response by targeting toll-like receptor 4. Cancer Chemother Pharmacol. 2019 Aug;84(2):287-298.

 

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