2017

Bassi GS, Dias DP, Franchin M, Talbot J, Reis DG, Menezes GB, Castania JA, Garcia-Cairasco N, Resstel L, Salgado HC, Cunha FQ, Cunha TM, Ulloa L, Kanashiro A. Modulation of Experimental Arthritis by Vagal Sensory and Central Brain Stimulation. Brain Behav Immun. 2017 Apr 6.

Becari C, Silva MA, Durand MT, Prado CM, Oliveira EB, Ribeiro MS, Salgado HC, Salgado MC, Tostes RC. Elastase-2, an angiotensin II-generating enzyme, contributes to increased Ang II in resistance arteries of mice with myocardial infarction. Br J Pharmacol. 2017 Feb 21.

Bertozzi MM, Rossaneis AC, Fattori V, Longhi-Balbinot DT, Freitas A, Cunha FQ, Alves-Filho JC, Cunha TM, Casagrande R, Verri WA Jr. Diosmin reduces chronic constriction injury-induced neuropathic pain in mice. Chem Biol Interact. 2017 Jun 15;273:180-189.

Braga TT, Correa-Costa M, Silva RC, Cruz MC, Hiyane MI, da Silva JS, Perez KR, Cuccovia IM, Camara NO. CCR2 contributes to the recruitment of monocytes and leads to kidney inflammation and fibrosis development. Inflammopharmacology. 2017 Feb 6.

Carlos D, Costa FR, Pereira CA, Rocha FA, Yaochite JN, Oliveira GG, Carneiro FS, Tostes RC, Ramos SG, Zamboni DS, Camara NO, Ryffel B, Silva JS. Mitochondrial DNA Activates the NLRP3 Inflammasome and Predisposes to Type 1 Diabetes in Murine Model. Front Immunol. 2017 Feb 27;8:164.

Côco H, Pernomian L, Pereira PC, Gomes MS, Marchi KC, Lopes AH, Cunha TM, Tirapelli CR, de Oliveira AM. Chronic restraint stress increases angiotensin II potency in the rat carotid: role of cyclooxygenases and reactive oxygen species. J Pharm Pharmacol. 2017 Jan;69(1):52-65.

Costa VV, Del Sarto JL, Rocha RF, Silva FR, Doria JG, Olmo IG, Marques RE, Queiroz-Junior CM, Foureaux G, Araújo JMS, Cramer A, Real ALCV, Ribeiro LS, Sardi SI, Ferreira AJ, Machado FS, de Oliveira AC, Teixeira AL, Nakaya HI, Souza DG, Ribeiro FM, Teixeira MM. N-Methyl-d-Aspartate (NMDA) Receptor Blockade Prevents Neuronal Death Induced by Zika Virus Infection. MBio. 2017 Apr 25;8(2).

Dal-Secco D, DalBó S, Lautherbach NES, Gava FN, Celes MRN, Benedet PO, Souza AH, Akinaga J, Lima V, Silva KP, Kiguti LRA, Rossi MA, Kettelhut IDC, Pupo AS, Cunha FQ, Assreuy J. Cardiac hyporesponsiveness in severe sepsis is associated with nitric oxide-dependent activation of G-protein receptor kinase. Am J Physiol Heart Circ Physiol. 2017 May 19:ajpheart.

Dalto VF, Assad RL, Crema MD, Louzada-Junior P, Nogueira-Barbosa MH. MRI assessment of bone marrow oedema in the sacroiliac joints of patients with spondyloarthritis: is the SPAIR T2w technique comparable to STIR? Eur Radiol. 2017 Feb 6.

de Aquino SG, Talbot J, Sônego F, Turato WM, Grespan R, Avila-Campos MJ, Cunha FQ, Cirelli JA. The aggravation of arthritis by periodontitis is dependent of IL-17 receptor A activation. J Clin Periodontol. 2017 May 12.

de Carvalho LM, Ngoumou G, Park JW, Ehmke N, Deigendesch N, Kitabayashi N, Melki I, Souza FFL, Tzschach A, Nogueira-Barbosa MH, Ferriani V, Louzada-Junior P, Junior WM, Lourenço CM, Horn D Prof, Kallinich T, Stenzel W, Hur S, Rice GI, Crow YJ. Musculoskeletal disease in MDA5-related type I interferonopathy – a Mendelian mimic of Jaccoud’s arthropathy. Arthritis Rheumatol. 2017 Jun 12.

de Oliveira LSS, de Araújo AA, de Araújo Júnior RF, Barboza CAG, Borges BCD, da Silva JSP. Low-level laser therapy (780 nm) combined with collagen sponge scaffold promotes repair of rat cranial critical-size defects and increases TGF-β, FGF-2, OPG/RANK and osteocalcin expression. Int J Exp Pathol. 2017 May 29.

Dias RG, Sampaio SC, Sant’Anna MB, Cunha FQ, Gutiérrez JM, Lomonte B, Cury Y, Picolo G. Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A(2): activation of endogenous phospholipases contributes to the pronociceptive effect. J Venom Anim Toxins Incl Trop Dis. 2017 Mar 23;23:18.

Eugenia Schroeder M, Russo S, Costa C, Hori J, Tiscornia I, Bollati-Fogolín M, Zamboni DS, Ferreira G, Cairoli E, Hill M. Pro-inflammatory Ca(++)-activated K(+) channels are inhibited by hydroxychloroquine. Sci Rep. 2017 May 15;7(1):1892.

Fattori V, Serafim KG, Zarpelon AC, Borghi SM, Pinho-Ribeiro FA, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA Jr. Differential regulation of oxidative stress and cytokine production by endothelin ET(A) and ET(B) receptors in superoxide anion-induced inflammation and pain in mice. J Drug Target. 2017 Mar;25(3):264-274.

Ferreira JV, Chaves GA, Marino BLB, Sousa KPA, Souza LR, Brito MFB, Teixeira HRC, da Silva CHTP, Santos CBR, Hage-Melim LIS. Cannabinoid Type 1 Receptor (CB1) Ligands with Therapeutic Potential for Withdrawal Syndrome in Chemical Dependents of Cannabis sativa. ChemMedChem. 2017 Apr 17.

Ferreira LR, Ferreira FM, Nakaya HI, Deng X, Cândido DD, de Oliveira LC, Billaud JN, Lanteri MC, Rigaud VO, Seielstad M, Kalil J, Fernandes F, Ribeiro AL, Sabino EC, Cunha-Neto E. Blood Gene Signatures of Chagas Cardiomyopathy With or Without Ventricular Dysfunction. J Infect Dis. 2017 Feb 1;215(3):387-395.

Franco LH, Fleuri AKA, Pellison NAC, Quirino GFS, Horta CV, Carvalho RVH, Oliveira SC, Zamboni DS. Autophagy downstream of endosomal Toll-like Receptors Signalingopha in Macrges is a Key Mechanism for Resistance to Leishmania major Infection. J Biol Chem. 2017 Jun 12.

Geraldo MV, Nakaya HI, Kimura ET. Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer. Oncotarget. 2017 Feb 7;8(6):9597-9607. .

Gonçalves AC, Ferreira LS, Manente FA, de Faria CM, Polesi MC, de Andrade CR, Zamboni DS, Carlos IZ. The NLRP3 inflammasome contributes to host protection during Sporothrix schenckii infection. Immunology. 2017 Jan 31.

Kanashiro A, Sônego F, Ferreira RG, Castanheira FV, Leite CA, Borges VF, Nascimento DC, Cólon DF, Alves-Filho JC, Ulloa L, Cunha FQ. Therapeutic potential and limitations of cholinergic anti-inflammatory pathway in sepsis. Pharmacol Res. 2017 Mar;117:1-8.

Kasturi SP, Kozlowski PA, Nakaya HI, Burger MC, Russo P, Pham M, Kovalenkov Y, Silveira EL, Havenar-Daughton C, Burton SL, Kilgore KM, Johnson MJ, Nabi R, Legere T, Sher ZJ, Chen X, Amara RR, Hunter E, Bosinger SE, Spearman P, Crotty S, Villinger F, Derdeyn CA, Wrammert J, Pulendran B. Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5α Restrictive Macaques. J Virol. 2017 Jan 31;91(4). pii: e01844-16.

Kazmin D, Nakaya HI, Lee EK, Johnson MJ, van der Most R, van den Berg RA, Ballou WR, Jongert E, Wille-Reece U, Ockenhouse C, Aderem A, Zak DE, Sadoff J, Hendriks J, Wrammert J, Ahmed R, Pulendran B. Systems analysis of protective immune responses to RTS,S malaria vaccination in humans. Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2425-2430.

Khalid KE, Nascimento MSL, Sacramento LA, Costa DL, Lima-Júnior DS, Carregaro V, da Silva JS. T1/ST2 deficient mice display protection against Leishmania infantum experimental infection. Acta Trop. 2017 Aug;172:1-6.

Lever M, Silveira EL, Nakaya HI. Systems Vaccinology Applied to DNA Vaccines: Perspective and Challenges. Curr Issues Mol Biol. 2017;22:1-16.

Li S, Sullivan NL, Rouphael N, Yu T, Banton S, Maddur MS, McCausland M, Chiu C, Canniff J, Dubey S, Liu K, Tran V, Hagan T, Duraisingham S, Wieland A, Mehta AK, Whitaker JA, Subramaniam S, Jones DP, Sette A, Vora K, Weinberg A, Mulligan MJ, Nakaya HI, Levin M, Ahmed R, Pulendran B. Metabolic Phenotypes of Response to Vaccination in Humans. Cell. 2017 May 18;169(5):862-877.e17.

Lucetti LT, Silva RO, Santana AP, de Melo Tavares B, Vale ML, Soares PM, de Lima Júnior FJ, Magalhães PJ, de Queiroz Cunha F, de Albuquerque Ribeiro R, Medeiros JR, Souza MH. Nitric Oxide and Hydrogen Sulfide Interact When Modulating Gastric Physiological Functions in Rodents. Dig Dis Sci. 2017 Jan;62(1):93-104.

Madeira MFM, Queiroz Junior CM, Corrêa JD, Werneck SMC, Machado FS, Cunha TM, Garlet GP, Teixeira MM, da Silva TA, Souza DG. The role of 5-lipoxygenase in Aggregatibacter actinomycetemcomitans-induced alveolar bone loss. J Clin Periodontol. 2017 Jun 1.

Maia PI, Carneiro ZA, Lopes CD, Oliveira CG, Silva JS, de Albuquerque S, Hagenbach A, Gust R, Deflon VM, Abram U. Organometallic gold(iii) complexes withhybrid SNS-donating thiosemicarbazone ligands: cytotoxicity and anti-Trypanosoma cruzi activity. Dalton Trans. 2017 Feb 21;46(8):2559-2571.

Martelli-Palomino G, Paoliello-Paschoalato AB, Crispim JC, Rassi DM, Oliveira RD, Louzada P, Lucisano-Valim YM, Donadi EA. DNA damage increase in peripheral neutrophils from patients with rheumatoid arthritis is associated with the disease activity and the presence of shared epitope. Clin Exp Rheumatol. 2017 Mar-Apr;35(2):247-254.

Mascarenhas DP, Zamboni DS. Inflammasome biology taught by Legionella pneumophila. J Leukoc Biol. 2017 Apr;101(4):841-849.

Massis LM, Assis-Marques MA, Castanheira FV, Capobianco YJ, Balestra AC, Escoll P, Wood RE, Manin GZ, Correa VM, Alves-Filho JC, Cunha FQ, Buchrieser C, Borges MC, Newton HJ, Zamboni DS. Legionella longbeachae Is Immunologically Silent and Highly Virulent In Vivo. J Infect Dis. 2017 Feb 1;215(3):440-451.

Nascimento DC, Melo PH, Piñeros AR, Ferreira RG, Colón DF, Donate PB, Castanheira FV, Gozzi A, Czaikoski PG, Niedbala W, Borges MC, Zamboni DS, Liew FY, Cunha FQ, Alves-Filho JC. IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population. Nat Commun. 2017 Apr 4;8:14919.

Parente JM, Pereira CA, Oliveira-Paula GH, Tanus-Santos JE, Tostes RC, Castro MM. Matrix Metalloproteinase (MMP)-2 Activity is Associated with Divergent Regulation of Calponin-1 in Conductance and Resistance Arteries in Hypertension-Induced Early Vascular Dysfunction and Remodelling. Basic Clin Pharmacol Toxicol. 2017 Apr 4.

Pereira AL, Dos Santos GB, Franco MS, Federico LB, da Silva CH, Santos CB. Molecular modeling and statistical analysis in the design of derivatives of human dipeptidyl peptidase IV. J Biomol Struct Dyn. 2017 Jan 24:1-17.

Pereira CA, Rodrigues FL, Ruginsk SG, Zanotto CZ, Rodrigues JA, Duarte DA, Costa-Neto CM, Resstel LB, Carneiro FS, Tostes RC. Chronic treatment with fluoxetine modulates vascular adrenergic responses by inhibition of pre- and post-synaptic mechanisms. Eur J Pharmacol. 2017 Apr 5;800:70-80.

Peres RS, Santos GB, Cecilio NT, Jabor VA, Niehues M, Torres BG, Buqui G, Silva CH, Costa TD, Lopes NP, Nonato MC, Ramalho FS, Louzada-Júnior P, Cunha TM, Cunha FQ, Emery FS, Alves-Filho JC. Lapachol, a compound targeting pyrimidine metabolism, ameliorates experimental autoimmune arthritis. Arthritis Res Ther. 2017 Mar 7;19(1):47.

Pernomian L, Gomes MS, Moreira JD, Silva CH, Rosa JM, Cardoso CR. New Horizons on Molecular Pharmacology Applied to Drug Discovery: When Resonance Overcomes Radioligand Binding. Current Radiopharmaceuticals, v. 9, p. xx-xxx, 2017.

Piñeros AR, Campos LW, Fonseca DM, Bertolini TB, Gembre AF, Prado RQ, Alves-Filho JC, Ramos SG, Russo M, Bonato VL. M2 macrophages or IL-33 treatment attenuate ongoing Mycobacterium tuberculosis infection. Sci Rep. 2017 Jan 27;7:41240.

Prada-Medina CA, Fukutani KF, Pavan Kumar N, Gil-Santana L, Babu S, Lichtenstein F, West K, Sivakumar S, Menon PA, Viswanathan V, Andrade BB, Nakaya HI, Kornfeld H. Systems Immunology of Diabetes-Tuberculosis Comorbidity Reveals Signatures of Disease Complications. Sci Rep. 2017 May 17;7(1):1999.

Ramos-Junior ES, Leite GA, Carmo-Silva CC, Taira TM, Neves KB, Colón DF, da Silva LA, Salvador SL, Tostes RC, Cunha FQ, Fukada SY. Adipokine Chemerin Bridges Metabolic Dyslipidemia and Alveolar Bone Loss in Mice. J Bone Miner Res. 2017 May;32(5):974-984.

Rodrigues FL, Fais RS, Pereira MGAG, Garcia-Cairasco N, Tostes RC, Carneiro FS. Erectile Dysfunction in Wistar Audiogenic Rats (WAR) is Associated with Increased Cavernosal Contraction and Decreased nNOS Protein Expression. Urology. 2017 May 5. pii: S0090-4295(17)30472-7.

Sacramento LA, da Costa JL, de Lima MH, Sampaio PA, Almeida RP, Cunha FQ, Silva JS, Carregaro V. Toll-Like Receptor 2 Is Required for Inflammatory Process Development during Leishmania infantum Infection. Front Microbiol. 2017 Feb 23;8:262.

Santos MB, de Oliveira DT, Cazzaniga RA, Varjão CS, Santos PLD, Santos MLB, Correia CB, Faria DR, Simon MDV, Silva JS, Dutra WO, Reed SG, Duthie MS, de Almeida RP, de Jesus AR. Distinct Roles of Th17 and Th1 Cells in Inflammatory Responses Associated with the Presentation of Paucibacillary Leprosy and Leprosy Reactions Th17 Immune Response in Leprosy. Scand J Immunol. 2017 Apr 20.

Silva JR, Lopes AH, Talbot J, Cecilio NT, Rossato MF, Silva RL, Souza GR, Silva CR, Lucas G, Fonseca BA, Arruda E, Alves-Filho JC, Cunha FQ, Cunha TM. Neuro-immune-glia interactions in the sensory ganglia account for the development of acute herpetic neuralgia. J Neurosci. 2017 Jun 2. pii: 2233-16.

Silva RL, Lopes AH, Guimarães RM, Cunha TM. CXCL1/CXCR2 signaling in pathological pain: Role in peripheral and central sensitization. Neurobiol Dis. 2017 Jun 3;105:109-116.

Simplicio JA, do Vale GT, Gonzaga NA, Leite LN, Hipólito UV, Pereira CA, Tostes RC, Tirapelli CR. Reactive oxygen species derived from NAD(P)H oxidase play a role on ethanol-induced hypertension and endothelial dysfunction in rat resistance arteries. J Physiol Biochem. 2017 Feb;73(1):5-16.

Souza MC, Fonseca DM, Kanashiro A, Benevides L, Medina TS, Dias MS, Andrade WA, Bonfá G, Silva MA, Gozzi A, Borges MC, Gazzinelli RT, Alves-Filho JC, Cunha FQ, Silva JS. Chronic Toxoplasma gondii Infection Exacerbates Secondary Polymicrobial Sepsis. Frontiers in Cellular and Infection Microbiology. 2017 Apr;7:116.

Spirlandeli AL, Dick-de-Paula I, Zamarioli A, Jorgetti V, Ramalho LNZ, Nogueira-Barbosa MH, Volpon JB, Jordão AA, Cunha FQ, Fukada SY, de Paula FJA. Hepatic Osteodystrophy: The Mechanism of Bone Loss in Hepatocellular Disease and the Effects of Pamidronate Treatment. Clinics (Sao Paulo). 2017 Apr;72(4):231-237.

Toson B, Dos Santos EJ, Adelino JE, Sandrin-Garcia P, Crovella S, Louzada-Júnior P, Oliveira RD, Pedroza LS, de Fátima Lobato Cunha Sauma M, de Lima CP, Barbosa FB, Brenol CV, Xavier RM, Chies JA, Veit TD. CCR5Δ32 and the genetic susceptibility to rheumatoid arthritis in admixed populations: a multicentre study. Rheumatology (Oxford). 2017 Jan 12. pii: kew398.

Trevelin SC, Carlos D, Beretta M, da Silva JS, Cunha FQ. Diabetes Mellitus and Sepsis: A Challenging Association. Shock. 2017 Mar;47(3):276-287.

Zucoloto AZ, Manchope MF, Staurengo-Ferrari L, Alves-Filho JC, Cunha TM, Antunes MM, Menezes GB, Cunha FQ, Casagrande R, Verri WA Jr. Probucol attenuates overt pain-like behavior and carrageenan-induced inflammatory hyperalgesia and leukocyte recruitment by inhibiting NF-кB activation and cytokine production without antioxidant effects. Inflamm Res. 2017 Jul;66(7):591-602.

Zucoloto AZ, Manchope MF, Staurengo-Ferrari L, Pinho-Ribeiro FA, Zarpelon AC, Saraiva ALL, Cecílio NT, Alves-Filho JC, Cunha TM, Menezes GB, Cunha FQ, Casagrande R, Verri WA Jr. Probucol attenuates lipopolysaccharide-induced leukocyte recruitment and inflammatory hyperalgesia: effect on NF-кB activation and cytokine production. Eur J Pharmacol. 2017 Aug 15;809:52-63.