2015

Akondy RS, Johnson PL, Nakaya HI, Edupuganti S, Mulligan MJ, Lawson B, Miller JD, Pulendran B, Antia R, Ahmed R. Initial viral load determines the magnitude of the human CD8 T cell response to yellow fever vaccination. Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):3050-5.

Almeida GT, Lage RC, Anderson L, Venancio TM, Nakaya HI, Miyasato PA, Rofatto HK, Zerlotini A, Nakano E, Oliveira G, Verjovski-Almeida S. Synergy of Omeprazole and Praziquantel In Vitro Treatment against Schistosoma mansoni Adult Worms. PLoS Negl Trop Dis. 2015 Sep 24;9(9):e0004086.

Alves Filho Fd, Cavalcanti PM, Passaglia Rde C, Ballejo G. Long-lasting endothelium-dependent relaxation of isolated arteries caused by an extract from the bark of Combretum leprosum. Einstein (Sao Paulo). 2015 Jul-Sep;13(3):395-403.

Angelo HD, Gomes Silva II, Oliveira RD, Louzada-Júnior P, Donadi EA, Crovella S, Maia MM, de Souza PR, Sandrin-Garcia P. Interleukin-18, interleukin-12B and interferon-γ gene polymorphisms in Brazilian patients with rheumatoid arthritis: a pilot study. Tissue Antigens. 2015 Oct;86(4):276-8.

Bassi GS, Brognara F, Castania JA, Talbot J, Cunha TM, Cunha FQ, Ulloa L, Kanashiro A, Dias DP, Salgado HC. Baroreflex activation in conscious rats modulates the joint inflammatory response via sympathetic function. Brain Behav Immun. 2015 Oct;49:140-7.

Benevides L, da Fonseca DM, Donate PB, Tiezzi DG, De Carvalho DD, de Andrade JM, Martins GA, Silva JS. IL17 Promotes Mammary Tumor Progression by Changing the Behavior of Tumor Cells and Eliciting Tumorigenic Neutrophils Recruitment. Cancer Res. 2015 Sep 15;75(18):3788-99.

Bomfim GF, Echem C, Martins CB, Costa TJ, Sartoretto SM, Dos Santos RA, Oliveira MA, Akamine EH, Fortes ZB, Tostes RC, Webb RC, Carvalho MH. Toll-like receptor 4 inhibition reduces vascular inflammation in spontaneously hypertensive rats. Life Sci. 2015 Feb 1;122:1-7.

Borghi SM, Pinho-Ribeiro FA, Zarpelon AC, Cunha TM, Alves-Filho JC, Ferreira SH, Cunha FQ, Casagrande R, Verri WA Jr. Interleukin-10 limits intense acute swimming-induced muscle mechanical hyperalgesia in mice. Exp Physiol. 2015 Apr 20;100(5):531-44.

Bruder-Nascimento T, Callera GE, Montezano AC, He Y, Antunes TT, Nguyen Dinh Cat A, Tostes RC, Touyz RM. Vascular injury in diabetic db/db mice is ameliorated by atorvastatin: role of Rac1/2-sensitive Nox-dependent pathways. Clin Sci (Lond). 2015 Apr;128(7):411-23.

Campo VL, Ivanova IM, Carvalho I, Lopes CD, Carneiro ZA, Saalbach G, Schenkman S, da Silva JS, Nepogodiev SA, Field RA. Click chemistry oligomerisation of azido-alkyne-functionalised galactose accesses triazole-linked linear oligomers and macrocycles that inhibit Trypanosoma cruzi macrophage invasion. Tetrahedron. 2015 Sep 30;71(39):7344-7353.

Cardoso CP, de Oliveira AJ, Botoni FA, Rezende IC, Alves-Filho JC, Cunha Fde Q, Estanislau Jde A, Magno LA, Rios-Santos F. Interleukin-10 rs2227307 and CXCR2 rs1126579 polymorphisms modulate the predisposition to septic shock. Mem Inst Oswaldo Cruz. 2015 Jun;110(4):453-60.

Carlos D, Yaochite JN, Rocha FA, Toso VD, Malmegrim KC, Ramos SG, Jamur MC, Oliver C, Camara NO, Andrade MV, Cunha FQ, Silva JS. Mast cells control insulitis and increase Treg cells to confer protection against STZ-induced type 1 diabetes in mice. Eur J Immunol. 2015 Oct;45(10):2873-85.

Carregaro V, Ribeiro JM, Valenzuela JG, Souza-Júnior DL, Costa DL, Oliveira CJ, Sacramento LA, Nascimento MS, Milanezi CM, Cunha FQ, Silva JS. Nucleosides present on phlebotomine saliva induce immunossuppression and promote the infection establishment. PLoS Negl Trop Dis. 2015 Apr 7;9(4):e0003600.

Carvalho NB, Oliveira FS, Marinho FA, de Almeida LA, Fahel JS, Báfica A, Rothfuchs AG, Zamboni DS, Caliari MV, Oliveira SC. Nucleotide-binding oligomerization domain-2 (NOD2) regulates type-1 cytokine responses to Mycobacterium avium but is not required for host control of infection. Microbes Infect. 2015 May;17(5):337-44.

Carvalho TT, Borghi SM, Pinho-Ribeiro FA, Mizokami SS, Cunha TM, Ferreira SH, Cunha FQ, Casagrande R, Verri WA Jr. Granulocyte-colony stimulating factor (G-CSF)-induced mechanical hyperalgesia in mice: Role for peripheral TNFα, IL-1β and IL-10. Eur J Pharmacol. 2015 Feb 15;749:62-72.

Cerqueira DM, Pereira MS, Silva AL, Cunha LD, Zamboni DS. Caspase-1 but Not Caspase-11 Is Required for NLRC4-Mediated Pyroptosis and Restriction of Infection by Flagellated Legionella Species in Mouse Macrophages and In Vivo. J Immunol. 2015 Sep 1;195(5):2303-11.

Chignalia AZ, Oliveira MA, Debbas V, Dull RO, Laurindo FR, Touyz RM, Carvalho MH, Fortes ZB, Tostes RC. Testosterone induces leucocyte migration by NADPH oxidase-driven ROS- and COX2-dependent mechanisms. Clin Sci (Lond). 2015 Jul;129(1):39-48.

Conte FP, Ferraris FK, Costa TE, Pacheco P, Seito LN, Verri WA Jr, Cunha FQ, Penido C, Henriques MG. Effect of gedunin on acute articular inflammation and hypernociception in mice. Molecules. 2015 Feb 3;20(2):2636-57.

Costa TJ, Ceravolo GS, dos Santos RA, de Oliveira MA, Araújo PX, Giaquinto LR, Tostes RC, Akamine EH, Fortes ZB, Dantas AP, Carvalho MH. Association of testosterone with estrogen abolishes the beneficial effects of estrogen treatment by increasing ROS generation in aorta endothelial cells. Am J Physiol Heart Circ Physiol. 2015 Apr 1;308(7):H723-32.

Cunha EL, Santos CF, Braga FS, Costa JS, Silva RC, Favacho HA, Hage-Melim LI, Carvalho JC, Silva CH, Santos CB. Computational Investigation of Antifungal Compounds Using Molecular Modeling and Prediction of ADME/Tox Properties. Journal of Computational and Theoretical Nanoscience, v. 12, p. 3682-3691, 2015.

Cunha LD, Ribeiro JM, Fernandes TD, Massis LM, Khoo CA, Moffatt JH, Newton HJ, Roy CR, Zamboni DS. Inhibition of inflammasome activation by Coxiella burnetii type IV secretion system effector IcaA. Nat Commun. 2015 Dec 21;6:10205.

da Costa TA, Silva MJ, Alves PM, Chica JE, Barcelos EZ, Giani MA, Garlet GP, da Silva JS, Rodrigues Júnior V, Rodrigues DB, Cardoso CR. Inflammation Biomarkers of Advanced Disease in Nongingival Tissues of Chronic Periodontitis Patients. Mediators Inflamm. 2015;2015:983782.

Da Mota LM, Cruz BA, Albuquerque CP, Gonçalves DL, Ieda MM, Pereira IA, Carvalho JF, Pinheiro GR, Bertolo MB, Silva NA, Louzada Júnior P, Xavier RM, Giorgi RD, Lima RA. Orientações preliminares da Sociedade Brasileira de Reumatologia para avaliação e tratamento da tuberculose infecção latente em pacientes com artrite reumatoide na indisponibilidade do teste tuberculínico. Revista Brasileira de Reumatologia (Impresso). 2015;55:390-393.

Da Mota LM, Cruz BA, Albuquerque CP, Gonçalves DL, Ieda MM, Pereira IA, Carvalho JF, Pinheiro GR, Bertolo MB, Pinto MR, Louzada Júnior P, Xavier RM, Giorgi RD, Lima RA. Posicionamento sobre o uso de tofacitinibe no algoritmo do Consenso 2012 da Sociedade Brasileira de Reumatologia para o tratamento da artrite reumatoide. Revista Brasileira de Reumatologia (Impresso). 2015;55:1-5.

da Mota LM, Cruz BA, de Albuquerque CP, Gonçalves D, Laurindo IM, Pereira IA, de Carvalho JF, Pinheiro Gda R, Bertolo MB, da Silva NA, Louzada Júnior P, Xavier RM, Giorgi RD, Lima RA. [Preliminary guidelines of the Brazilian Society of Rheumatology for evaluation and treatment of tuberculosis latent infection in patients with rheumatoid arthritis, in face of unavailability of the tuberculin skin test]. Rev Bras Reumatol. 2015 Jul-Aug;55(4):390-3.

da Mota LM, Cruz BA, de Albuquerque CP, Gonçalves DP, Laurindo IM, Pereira IA, de Carvalho JF, Pinheiro Gda R, Bertolo MB, Pinto MR, Louzada-Junior P, Xavier RM, Giorgi RD, Lima RA. Update on the 2012 Brazilian Society of Rheumatology Guidelines for the treatment of rheumatoid arthritis: position on the use of tofacitinib. Rev Bras Reumatol. 2015 Nov-Dec;55(6):512-21.

de Andrade P, Galo OA, Carvalho MR, Lopes CD, Carneiro ZA, Sesti-Costa R, de Melo EB, Silva JS, Carvalho I. 1,2,3-Triazole-based analogue of benznidazole displays remarkable activity against Trypanosoma cruzi. Bioorg Med Chem. 2015 Nov 1;23(21):6815-26.

de Melo FM, Braga CJ, Pereira FV, Maricato JT, Origassa CS, Souza MF, Melo AC, Silva P, Tomaz SL, Gimenes KP, Scutti JA, Juliano MA, Zamboni DS, Câmara NO, Travassos LR, Ferreira LC, Rodrigues EG. Anti-metastatic immunotherapy based on mucosal administration of flagellin and immunomodulatory P10. Immunol Cell Biol. 2015 Jan;93(1):86-98.

de Melo Nunes R, Martins MR, da Silva Junior FS, de Melo Leite AC, Girão VC, de Queiroz Cunha F, Marinho AL, Pinto AC, Rocha FA. Strontium ranelate analgesia in arthritis models is associated to decreased cytokine release and opioid-dependent mechanisms. Inflamm Res. 2015 Oct;64(10):781-7.

Dias FC, Mendes-Junior CT, Silva MC, Tristão FS, Dellalibera-Joviliano R, Moreau P, Soares EG, Menezes JG, Schmidt A, Dantas RO, Marin-Neto JA, Silva JS, Donadi EA. Human leucocyte antigen-G (HLA-G) and its murine functional homolog Qa2 in the Trypanosoma cruzi Infection. Mediators Inflamm. 2015;2015:595829.

Fafá BP, Louzada-Junior P, Titton DC, Zandonade E, Ranza R, Laurindo I, Peçanha P, Ranzolin A, Hayata AL, Duarte A, Silveira IG, Costa I, Macieira JC, Guedes-Barbosa LS, Bertolo MB, Sauma MF, Silva MB, Freire M, Scheinberg MA, Fernandes V, Bianchi W, Miranda JR, Pinheiro GR, Carvalho HM, Brenol CV, Pereira IA, de Castro GR, de Morais JC, Oliveira SK, de Abreu MM, Toledo RA, Pinheiro MM, Vieira WP, Valim V. Drug survival and causes of discontinuation of the first anti-TNF in ankylosing spondylitis compared with rheumatoid arthritis: analysis from BIOBADABRASIL. Clin Rheumatol. 2015 May;34(5):921-7.

Fattori V, Pinho-Ribeiro FA, Borghi SM, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA Jr. Curcumin inhibits superoxide anion-induced pain-like behavior and leukocyte recruitment by increasing Nrf2 expression and reducing NF-κB activation. Inflamm Res. 2015 Dec;64(12):993-1003.

Ferreira NS, Cau SB, Silva MA, Manzato CP, Mestriner FL, Matsumoto T, Carneiro FS, Tostes RC. Diabetes impairs the vascular effects of aldosterone mediated by G protein-coupled estrogen receptor activation. Front Pharmacol. 2015 Mar 2;6:34.

Fonseca MD, Cunha FQ, Kashfi K, Cunha TM. NOSH-aspirin (NBS-1120), a dual nitric oxide and hydrogen sulfide-releasing hybrid, reduces inflammatory pain. Pharmacol Res Perspect. 2015 Jun;3(3):e00133.

Franca R, Vieira SM, Talbot J, Peres RS, Pinto LG, Zamboni DS, Louzada-Junior P, Cunha FQ, Cunha TM. Expression and activity of NOD1 and NOD2/RIPK2 signalling in mononuclear cells from patients with rheumatoid arthritis. Scand J Rheumatol. 2015 Jul 45:8-12.

Freitas CS, Roveda AC Jr, Truzzi DR, Garcia AC, Cunha TM, Cunha FQ, Franco DW. Anti-inflammatory and Anti-nociceptive Activity of Ruthenium Complexes with Isonicotinic and Nicotinic Acids (Niacin) as Ligands. J Med Chem. 2015 Jun 11;58(11):4439-48.

Galvani RG, Lemos R, Areal RB, Salvador PA, Zamboni DS, Wanderley JL, Bonomo A. Disease severity and mortality can be independently regulated in a mouse model of experimental graft versus host disease. PLoS One. 2015 Feb 2;10(2):e0118079.

Gaspar-Elsas MI, Queto T, Masid-de-Brito D, Vieira BM, de Luca B, Cunha FQ, Xavier-Elsas P. α-Galactosylceramide suppresses murine eosinophil production through interferon-γ-dependent induction of NO synthase and CD95. Br J Pharmacol. 2015 Jul;172(13):3313-25.

Gonçalves L, Vieira J, Silva N, Santos C, Braga F, Costa J, Macêdo W, Silva C, Hage-Melim LI, Santos C. A QSAR Study of New Caffeine Derivatives with Epithelial Anticancer Activity. British Journal of Pharmaceutical Research, v. 7, p. 122-139, 2015.

Hagan T, Nakaya HI, Subramaniam S, Pulendran B. Systems vaccinology: Enabling rational vaccine design with. 2015 Sep 29;33(40):5294-301.

Ketelut-Carneiro N, Silva GK, Rocha FA, Milanezi CM, Cavalcanti-Neto FF, Zamboni DS, Silva JS. IL-18 triggered by the Nlrp3 inflammasome induces host innate resistance in a pulmonary model of fungal infection. J Immunol. 2015 May 1;194(9):4507-17.

Kian D, Lancheros CA, Damiani IA, Fernandes TZ, Pinge-Filho P, Santos MR, Silveira JF, Nakamura CV, Silva JS, Yamada-Ogatta SF, Yamauchi LM. Molecular Characterization of Trypanosoma cruzi Tc8.2 Gene Indicates Two Differential Locations for the Encoded Protein in Epimastigote and Trypomastigote Forms. Korean J Parasitol. 2015 Aug;53(4):483-8.

Leite CA, Alencar VT, Melo DL, Mota JM, Melo PH, Mourão LT, Wong DV, Magalhães PJ, Santos AA, Brito GA, Lima-Júnior RC, Cunha FQ, Ribeiro RA. Target Inhibition of IL-1 Receptor Prevents Ifosfamide Induced Hemorrhagic Cystitis in Mice. J Urol. 2015 Dec;194(6):1777-86.

Leite FR, de Aquino SG, Guimarães MR, Cirelli JA, Zamboni DS, Silva JS, Junior CR. Relevance of the myeloid differentiation factor 88 (MyD88) on RANKL, OPG, and nod expressions induced by TLR and IL-1R signaling in bone marrow stromal cells. Inflammation. 2015 Feb;38(1):1-8.

Lima CX, Souza DG, Amaral FA, Fagundes CT, Rodrigues IP, Alves-Filho JC, Kosco-Vilbois M, Ferlin W, Shang L, Elson G, Teixeira MM. Therapeutic Effects of Treatment with Anti-TLR2 and Anti-TLR4 Monoclonal Antibodies in Polymicrobial Sepsis. PLoS One. 2015 Jul 6;10(7):e0132336.

Lima LG, Bonardi JM, Campos GO, Bertani RF, Scher LM, Louzada-Junior P, Moriguti JC, Ferriolli E, Lima NK. Effect of aerobic training and aerobic and resistance training on the inflammatory status of hypertensive older adults. Aging Clin Exp Res. 2015 Aug;27(4):483-9.

Lisboa SF, Gomes FV, Silva AL, Uliana DL, Camargo LH, Guimarães FS, Cunha FQ, Joca SR, Resstel LB. Increased Contextual Fear Conditioning in iNOS Knockout Mice: Additional Evidence for the Involvement of Nitric Oxide in Stress-Related Disorders and Contribution of the Endocannabinoid System. Int J Neuropsychopharmacol. 2015 Jan 24;18(8). pii: pyv005.

Lopes AH, Talbot J, Silva RL, Lima JB, França RO, Verri WA Jr, Mascarenhas DP, Ryffel B, Cunha FQ, Zamboni DS, Cunha TM. Peripheral NLCR4 inflammasome participates in the genesis of acute inflammatory pain. Pain. 2015 Mar;156(3):451-9.

Lopes RA, Neves KB, Tostes RC, Montezano AC, Touyz RM. Downregulation of Nuclear Factor Erythroid 2-Related Factor and Associated Antioxidant Genes Contributes to Redox-Sensitive Vascular Dysfunction in Hypertension. Hypertension. 2015 Dec;66(6):1240-50.

Mascarenhas DP, Pereira MS, Manin GZ, Hori JI, Zamboni DS. Interleukin 1 receptor-driven neutrophil recruitment accounts to MyD88-dependent pulmonary clearance of legionella pneumophila infection in vivo. J Infect Dis. 2015 Jan 15;211(2):322-30.

Matsumoto T, Goulopoulou S, Taguchi K, Tostes RC, Kobayashi T. Constrictor prostanoids and uridine adenosine tetraphosphate: vascular mediators and therapeutic targets in hypertension and diabetes. Br J Pharmacol. 2015 Aug;172(16):3980-4001.

Molinaro R, Pecli C, Guilherme RF, Alves-Filho JC, Cunha FQ, Canetti C, Kunkel SL, Bozza MT, Benjamim CF. CCR4 Controls the Suppressive Effects of Regulatory T Cells on Early and Late Events during Severe Sepsis. PLoS One. 2015 Jul 21;10(7):e0133227.

Moreira JD, Pernomian L, Gomes MS, Pernomian L, Moreira RP, do Prado AF, da Silva CH, de Oliveira AM. Acute restraint stress increases carotid reactivity in type-I diabetic rats by enhancing Nox4/NADPH oxidase functionality. Eur J Pharmacol. 2015 Oct 15;765:503-16.

Mota LM, Cruz BA, Brenol CV, Pollak DF, Pinheiro Gda R, Laurindo IM, Pereira IA, Carvalho JF, Bertolo MB, Pinheiro Mde M, Freitas MV, Silva NA, Louzada-Júnior P, Sampaio-Barros PD, Giorgi RD, Lima RA, Andrade LE. [Safe use of biological therapies for the treatment of rheumatoid arthritis and spondyloarthritides]. Rev Bras Reumatol. 2015 May-Jun;55(3):281-309.

Mota LM, Cruz BA, Brenol CV, Pollak DF, Pinheiro GR, Laurindo IM, Pereira IA, Carvalho JF, Bertolo MB, Pinheiro MM, Freitas MV, Silva NA, Louzada-Júnior P, Sampaio PD, Giorgi RD, Lima RA, Andrade LE. Segurança do uso de terapias biológicas para o tratamento de artrite reumatoide e espondiloartrites. Revista Brasileira de Reumatologia (Impresso). 2015;55:281-309.

Moura JF, Mota JM, Leite CA, Wong DV, Bezerra NP, Brito GA, Lima V, Cunha FQ, Ribeiro RA. A novel model of megavoltage radiation-induced oral mucositis in hamsters: Role of inflammatory cytokines and nitric oxide. Int J Radiat Biol. 2015 Jun;91(6):500-9.

Nakaya HI, Bruna-Romero O. Is the gut microbiome key to modulating vaccine efficacy? Expert Rev Vaccines. 2015 Jun;14(6):777-9.

Nakaya HI, Hagan T, Duraisingham SS, Lee EK, Kwissa M, Rouphael N, Frasca D, Gersten M, Mehta AK, Gaujoux R, Li GM, Gupta S, Ahmed R, Mulligan MJ, Shen-Orr S, Blomberg BB, Subramaniam S, Pulendran B. Systems Analysis of Immunity to Influenza Vaccination across Multiple Years and in Diverse Populations Reveals Shared Molecular Signatures. Immunity. 2015 Dec 15;43(6):1186-98.

Nakaya HI, Pulendran B. Vaccinology in the era of high-throughput biology. Philos Trans R Soc Lond B Biol Sci. 2015 Jun 19;370(1671). pii: 20140146.

Nascimento MS, Carregaro V, Lima-Júnior DS, Costa DL, Ryffel B, Duthie MS, de Jesus A, de Almeida RP, da Silva JS. Interleukin 17A acts synergistically with interferon γ to promote protection against Leishmania infantum infection. J Infect Dis. 2015 Mar 15;211(6):1015-26.

Navarro IC, Ferreira FM, Nakaya HI, Baron MA, Vilar-Pereira G, Pereira IR, Silva AM, Real JM, De Brito T, Chevillard C, Lannes-Vieira J, Kalil J, Cunha-Neto E, Ferreira LR. MicroRNA Transcriptome Profiling in Heart of Trypanosoma cruzi-Infected Mice: Parasitological and Cardiological Outcomes. PLoS Negl Trop Dis. 2015 Jun 18;9(6):e0003828.

Neves KB, Nguyen Dinh Cat A, Lopes RA, Rios FJ, Anagnostopoulou A, Lobato NS, de Oliveira AM, Tostes RC, Montezano AC, Touyz RM. Chemerin Regulates Crosstalk Between Adipocytes and Vascular Cells Through Nox. Hypertension. 2015 Sep;66(3):657-66.

Parra RS, Lopes AH, Carreira EU, Feitosa MR, Cunha FQ, Garcia SB, Cunha TM, da Rocha JJ, Féres O. Hyperbaric oxygen therapy ameliorates TNBS-induced acute distal colitis in rats. Med Gas Res. 2015 Apr 16;5:6.

Patricio ES, Costa R, Figueiredo CP, Gers-Barlag K, Bicca MA, Manjavachi MN, Segat GC, Gentry C, Luiz AP, Fernandes ES, Cunha TM, Bevan S, Calixto JB. Mechanisms Underlying the Scratching Behavior Induced by the Activation of Proteinase-Activated Receptor-4 in Mice. J Invest Dermatol. 2015 Oct;135(10):2484-91.

Pereira CA, Ferreira NS, Mestriner FL, Antunes-Rodrigues J, Evora PR, Resstel LB, Carneiro FS, Tostes RC. Chronic fluoxetine treatment increases NO bioavailability and calcium-sensitive potassium channels activation in rat mesenteric resistance arteries. Eur J Pharmacol. 2015 Oct 15;765:375-83.

Peres RS, Liew FY, Talbot J, Carregaro V, Oliveira RD, Almeida SL, França RF, Donate PB, Pinto LG, Ferreira FI, Costa DL, Demarque DP, Gouvea DR, Lopes NP, Queiroz RH, Silva JS, Figueiredo F, Alves-Filho JC, Cunha TM, Ferreira SH, Louzada-Junior P, Cunha FQ. Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis. Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2509-14.

Pernomian L, da Silva CH. Current basis for discovery and development of aryl hydrocarbon receptor antagonists for experimental and therapeutic use in atherosclerosis. Eur J Pharmacol. 2015 Oct 5;764:118-23.

Pernomian L, do Prado AF, Gomes MS, Pernomian L, da Silva CH, Gerlach RF, de Oliveira AM. MAS receptors mediate vasoprotective and atheroprotective effects of candesartan upon the recovery of vascular angiotensin-converting enzyme 2-angiotensin-(1-7)-MAS axis functionality. Eur J Pharmacol. 2015 Oct 5;764:173-88.

Pernomian L, Pernomian L, Gomes MS, da Silva CH. Pharmacological significance of the interplay between angiotensin receptors: MAS receptors as putative final mediators of the effects elicited by angiotensin AT1 receptors antagonists. Eur J Pharmacol. 2015 Dec 15;769:143-6.

Picanço L, Castro L, Pinheiro A, Silva K, Souza L, Braga F, Silva C, Santos C, Hage-Melim LI. Study of Molecular Docking, Physicochemical and Pharmacokinetic Properties of GSK-3β Inhibitors. British Journal of Pharmaceutical Research, v. 7, p. 152-175, 2015.

Pinheiro AA, Silva KR, Silva AE, Braga FS, Silva CH, Santos CB, Hage-Melim LI. In silico Identification of Novel Potential BACE-1 Inhibitors for Alzheimer?s Disease Treatment: Molecular Docking, Pharmacophore Modeling and Activity and Synthetic Accessibility Predictions. British Journal of Pharmaceutical Research, v. 7, p. 217-229, 2015.

Pinto LG, Talbot J, Peres RS, Franca RF, Ferreira SH, Ryffel B, Aves-Filho JC, Figueiredo F, Cunha TM, Cunha FQ. Joint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1β production. Arthritis Res Ther. 2015 Sep 2;17:235.

Quadros AU, Pinto LG, Fonseca MM, Kusuda R, Cunha FQ, Cunha TM. Dynamic weight bearing is an efficient and predictable method for evaluation of arthritic nociception and its pathophysiological mechanisms in mice. Sci Rep. 2015 Oct 29;5:14648.

Ramos-Junior ES, Morandini AC, Almeida-da-Silva CL, Franco EJ, Potempa J, Nguyen KA, Oliveira AC, Zamboni DS, Ojcius DM, Scharfstein J, Coutinho-Silva R. A Dual Role for P2X7 Receptor during Porphyromonas gingivalis Infection. J Dent Res. 2015 Sep;94(9):1233-42.

Ranza R, Laurindo I, Titton D, Barbosa L, Bertolo M, Bertaccini J, Brenol C, Carvalho H, Castro G, Cecconi M, Costa I, Duarte A, Fernandes V, Freire M, Louzada P, Macieira J, Miranda J, Pereira I, Pinheiro G, Pinheiro M, Sauma M, Silva M, Toledo R, Valin V, Vieira W, et al. SAT0362-Incidence of Adverse Events in Patients with Rheumatoid Arthritis and Spondyloarthritis Exposed to Anti-Tnf Therapy. Annals of the Rheumatic Diseases. 2015;74:790.2-790

Rodrigues FL, Fais RS, Tostes RC, Carneiro FS. There is a link between erectile dysfunction and heart failure: it could be inflammation. Curr Drug Targets. 2015;16(5):442-50.

Rodrigues FL, Silva LE, Hott SC, Bomfim GF, da Silva CA, Fazan R Jr, Resstel LB, Tostes RC, Carneiro FS. Toll-like receptor 9 plays a key role in the autonomic cardiac and baroreflex control of arterial pressure. Am J Physiol Regul Integr Comp Physiol. 2015 Apr 15;308(8):R714-23.

Rondinoni C, Zanatta DP, Souza-Zinader J, Louzada Junior P, Menezes PR, Santos AC, Del-Ben CM. P.3.f.024 Tract-based statistics in first episode psychosis: preliminary results depending on substance abuse comorbidity. European Neuropsychopharmacology. 2015;25:S549-S550.

Ruiz-Miyazawa KW, Pinho-Ribeiro FA, Zarpelon AC, Staurengo-Ferrari L, Silva RL, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA Jr. Vinpocetine reduces lipopolysaccharide-induced inflammatory pain and neutrophil recruitment in mice by targeting oxidative stress, cytokines and NF-κB. Chem Biol Interact. 2015 Jul 25;237:9-17.

Sacramento L, Trevelin SC, Nascimento MS, Lima-Jùnior DS, Costa DL, Almeida RP, Cunha FQ, Silva JS, Carregaro V. Toll-like receptor 9 signaling in dendritic cells regulates neutrophil recruitment to inflammatory foci following Leishmania infantum infection. Infect Immun. 2015 Dec;83(12):4604-16.

Santos CB, Lobato CC, Braga FS, Costa Jda S, Favacho HA, Carvalho JC, Macedo WJ, Brasil Ddo S, Silva CH, Silva Hage-Melim LI. Rational Design of Antimalarial Drugs Using Molecular Modeling and Statistical Analysis. Curr Pharm Des. 2015;21(28):4112-27.

Santos CB, Lobato CC, Braga FS, Costa JS, Favacho HA, Carvalho JC, Macedo WJ, Brasil DS, Silva CH, Hage-Melim LI. Rational Design of Antimalarial Drugs Using Molecular Modeling and Statistical Analysis. Current Pharmaceutical Design (Print), v. 21, p. 4112-4127, 2015.

Serafim KG, Navarro SA, Zarpelon AC, Pinho-Ribeiro FA, Fattori V, Cunha TM, Alves-Filho JC, Cunha FQ, Casagrande R, Verri WA Jr. Bosentan, a mixed endothelin receptor antagonist, inhibits superoxide anion-induced pain and inflammation in mice. Naunyn Schmiedebergs Arch Pharmacol. 2015 Nov;388(11):1211-21. s vascular dysfunction in type 2 diabetic mice by decreasing oxidative stress and restoring NO/GC signaling. Front Physiol. 2015 Oct 5;6:269.

Silva MA, Cau SB, Lopes RA, Manzato CP, Neves KB, Bruder-Nascimento T, Mestriner FL, Montezano AC, Nguyen Dinh Cat A, Touyz RM, Tostes RC. Mineralocorticoid receptor blockade prevents vascular remodelling in a rodent model of type 2 diabetes mellitus. Clin Sci (Lond). 2015 Oct;129(7):533-45.

Silva NS, Santos CF, Goncalves LK, Braga FS, Silva RC, Costa JS, Silva CH, Brasil DS, Hage-Melim LI, Santos CB. Molecular Modeling of the Major Compounds of Sesquiterpenes Class in Copaiba Oil-resin. British Journal of Pharmaceutical Research, v. 7, p. 247-263, 2015.

Silva RL, Lopes AH, França RO, Vieira SM, Silva EC, Amorim RC, Cunha FQ, Pohlit AM, Cunha TM. The quassinoid isobrucein B reduces inflammatory hyperalgesia and cytokine production by post-transcriptional modulation. J Nat Prod. 2015 Feb 27;78(2):241-9.

Souza GR, Cunha TM, Silva RL, Lotufo CM, Verri WA Jr, Funez MI, Villarreal CF, Talbot J, Sousa LP, Parada CA, Cunha FQ, Ferreira SH. Involvement of nuclear factor kappa B in the maintenance of persistent inflammatory hypernociception. Pharmacol Biochem Behav. 2015 Jul;134:49-56.

Talbot J, Bianchini FJ, Nascimento DC, Oliveira RD, Souto FO, Pinto LG, Peres RS, Silva JR, Almeida SC, Louzada-Junior P, Cunha TM, Cunha FQ, Alves-Filho JC. CCR2 Expression in Neutrophils Plays a Critical Role in Their Migration Into the Joints in Rheumatoid Arthritis. Arthritis Rheumatol. 2015 Jul;67(7):1751-9.

Toller-Kawahisa JE, Canicoba NC, Venancio VP, Kawahisa R, Antunes LM, Cunha TM, Marzocchi-Machado CM. Systemic lupus erythematosus onset in lupus-prone B6.MRL/lpr mice Is influenced by weight gain and Is preceded by an increase in neutrophil oxidative burst activity. Free Radic Biol Med. 2015 Sep;86:362-73.

Uren PJ, Vo DT, de Araujo PR, Pötschke R, Burns SC, Bahrami-Samani E, Qiao M, de Sousa Abreu R, Nakaya HI, Correa BR, Kühnöl C, Ule J, Martindale JL, Abdelmohsen K, Gorospe M, Smith AD, Penalva LO. RNA-Binding Protein Musashi1 Is a Central Regulator of Adhesion Pathways in Glioblastoma. Mol Cell Biol. 2015 Sep 1;35(17):2965-78.

Vaz ER, Fujimura PT, Araujo GR, da Silva CA, Silva RL, Cunha TM, Lopes-Ferreira M, Lima C, Ferreira MJ, Cunha-Junior JP, Taketomi EA, Goulart LR, Ueira-Vieira C. A Short Peptide That Mimics the Binding Domain of TGF-β1 Presents Potent Anti-Inflammatory Activity. PLoS One. 2015 Aug 27;10(8):e0136116.

Veras FP, Peres RS, Saraiva AL, Pinto LG, Louzada-Junior P, Cunha TM, Paschoal JA, Cunha FQ, Alves-Filho JC. Fructose 1,6-bisphosphate, a high-energy intermediate of glycolysis, attenuates experimental arthritis by activating anti-inflammatory adenosinergic pathway. Sci Rep. 2015 Oct 19;5:15171.

Wong DV, Lima-Júnior RC, Carvalho CB, Borges VF, Wanderley CW, Bem AX, Leite CA, Teixeira MA, Batista GL, Silva RL, Cunha TM, Brito GA, Almeida PR, Cunha FQ, Ribeiro RA. The Adaptor Protein Myd88 Is a Key Signaling Molecule in the Pathogenesis of Irinotecan-Induced Intestinal Mucositis. PLoS One. 2015 Oct 6;10(10):e0139985.

Xavier-Elsas P, de Luca B, Queto T, Vieira BM, Masid-de-Brito D, Dahab EC, Alves Filho JC, Cunha FQ, Gaspar-Elsas MI. Blockage of Eosinopoiesis by IL-17A Is Prevented by Cytokine and Lipid Mediators of Allergic Inflammation. Mediators Inflamm. 2015;2015:968932.

Yamacita-Borin FY, Zarpelon AC, Pinho-Ribeiro FA, Fattori V, Alves-Filho JC, Cunha FQ, Cunha TM, Casagrande R, Verri WA Jr. Superoxide anion-induced pain and inflammation depends on TNFα/TNFR1 signaling in mice. Neurosci Lett. 2015 Sep25;605:53-8.

Zamboni DS, Lima-Junior DS. Inflammasomes in host response to protozoan parasites. Immunol Rev. 2015 May;265(1):156-71.