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Publicações - 2014

Aguiar CJ, Rocha-Franco JA, Sousa PA, Santos AK, Ladeira M, Rocha-Resende C, Ladeira LO, Resende RR, Botoni FA, Barrouin Melo M, Lima CX, Carballido JM, Cunha TM, Menezes GB, Guatimosim S, Leite MF. Succinate causes pathological cardiomyocyte hypertrophy through GPR91 activation. Cell Commun Signal. 2014 Dec 24;12:78. doi: 10.1186/s12964-014-0078-2. PMID: 25539979; PMCID: PMC4296677. Clique Aqui

Arifa RD, Madeira MF, de Paula TP, Lima RL, Tavares LD, Menezes-Garcia Z, Fagundes CT, Rachid MA, Ryffel B, Zamboni DS, Teixeira MM, Souza DG. Inflammasome activation is reactive oxygen species dependent and mediates irinotecan-induced mucositis through IL-1β and IL-18 in mice. Am J Pathol. 2014 Jul;184(7):2023-34. doi: 10.1016/j.ajpath.2014.03.012. PMID: 24952429. Clique Aqui

Ataide MA, Andrade WA, Zamboni DS, Wang D, Souza Mdo C, Franklin BS, Elian S, Martins FS, Pereira D, Reed G, Fitzgerald KA, Golenbock DT, Gazzinelli RT. Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection. PLoS Pathog. 2014 Jan;10(1):e1003885. doi: 10.1371/journal.ppat.1003885. Epub 2014 Jan 16. Erratum in: PLoS Pathog. 2014 Jun;10(6):e1004258. PMID: 24453977; PMCID: PMC3894209. Clique Aqui

Barbour M, Allan D, Xu H, Pei C, Chen M, Niedbala W, Fukada SY, Besnard AG, Alves-Filho JC, Tong X, Forrester JV, Liew FY, Jiang HR. IL-33 attenuates the development of experimental autoimmune uveitis. Eur J Immunol. 2014 Nov;44(11):3320-9. doi: 10.1002/eji.201444671. Epub 2014 Oct 18. PMID: 25116404; PMCID: PMC4449115. Clique Aqui

Barragán-Iglesias P, Rocha-González HI, Pineda-Farias JB, Murbartián J, Godínez-Chaparro B, Reinach PS, Cunha TM, Cunha FQ, Granados-Soto V. Inhibition of peripheral anion exchanger 3 decreases formalin-induced pain. Eur J Pharmacol. 2014 Sep 5;738:91-100. doi: 10.1016/j.ejphar.2014.05.029. Epub 2014 May 27. PMID: 24877687. Clique Aqui

Belai EB, de Oliveira CE, Gasparoto TH, Ramos RN, Torres SA, Garlet GP, Cavassani KA, Silva JS, Campanelli AP. PD-1 blockage delays murine squamous cell carcinoma development. Carcinogenesis. 2014 Feb;35(2):424-31. doi: 10.1093/carcin/bgt305. Epub 2013 Sep 12. PMID: 24031027. Clique Aqui

Bomfim GF, Echem C, Martins CB, Costa TJ, Sartoretto SM, Dos Santos RA, Oliveira MA, Akamine EH, Fortes ZB, Tostes RC, Webb RC, Carvalho MH. Toll-like receptor 4 inhibition reduces vascular inflammation in spontaneously hypertensive rats. Life Sci. 2015 Feb 1;122:1-7. doi: 10.1016/j.lfs.2014.12.001. Epub 2014 Dec 11. PMID: 25498891; PMCID: PMC4790807. Clique Aqui

Bonfá G, Benevides L, Souza Mdo C, Fonseca DM, Mineo TW, Rossi MA, Silva NM, Silva JS, de Barros Cardoso CR. CCR5 controls immune and metabolic functions during Toxoplasma gondii infection. PLoS One. 2014 Aug 13;9(8):e104736. doi: 10.1371/journal.pone.0104736. PMID: 25119429; PMCID: PMC4132074. Clique Aqui

Borghi SM, Zarpelon AC, Pinho-Ribeiro FA, Cardoso RD, Cunha TM, Alves-Filho JC, Ferreira SH, Cunha FQ, Casagrande R, Verri WA Jr. Targeting interleukin-1β reduces intense acute swimming-induced muscle mechanical hyperalgesia in mice. J Pharm Pharmacol. 2014 Jul;66(7):1009-20. doi: 10.1111/jphp.12226. Epub 2014 Feb 13. PMID: 24697255. Clique Aqui

Borghi SM, Zarpelon AC, Pinho-Ribeiro FA, Cardoso RD, Martins-Pinge MC, Tatakihara RI, Cunha TM, Ferreira SH, Cunha FQ, Casagrande R, Verri WA Jr. Role of TNF-α/TNFR1 in intense acute swimming-induced delayed onset muscle soreness in mice. Physiol Behav. 2014 Apr 10;128:277-87. doi: 10.1016/j.physbeh.2014.01.023. Epub 2014 Feb 8. PMID: 24518865. Clique Aqui

Bruder-Nascimento T, Chinnasamy P, Riascos-Bernal DF, Cau SB, Callera GE, Touyz RM, Tostes RC, Sibinga NE. Angiotensin II induces Fat1 expression/activation and vascular smooth muscle cell migration via Nox1-dependent reactive oxygen species generation. J Mol Cell Cardiol. 2014 Jan;66:18-26. doi: 10.1016/j.yjmcc.2013.10.013. PMID: 24445059; PMCID: PMC3943818. Clique Aqui

Bruder-Nascimento T, da Silva MA, Tostes RC. The involvement of aldosterone on vascular insulin resistance: implications in obesity and type 2 diabetes. Diabetol Metab Syndr. 2014 Aug 24;6(1):90. doi: 10.1186/1758-5996-6-90. PMID: 25352918; PMCID: PMC4210491. Clique Aqui

Calil IL, Zarpelon AC, Guerrero AT, Alves-Filho JC, Ferreira SH, Cunha FQ, Cunha TM, Verri WA Jr. Lipopolysaccharide induces inflammatory hyperalgesia triggering a TLR4/MyD88-dependent cytokine cascade in the mice paw. PLoS One. 2014 Mar 3;9(3):e90013. doi: 10.1371/journal.pone.0090013. PMID: 24595131; PMCID: PMC3940714. Clique Aqui

Canavaci AM, Sorgi CA, Martins VP, Morais FR, de Sousa ÉV, Trindade BC, Cunha FQ, Rossi MA, Aronoff DM, Faccioli LH, Nomizo A. The acute phase of Trypanosoma cruzi infection is attenuated in 5-lipoxygenase-deficient mice. Mediators Inflamm. 2014;2014:893634. doi: 10.1155/2014/893634. Epub 2014 Aug 3. PMID: 25165415; PMCID: PMC4137569. Clique Aqui

Carmona F, Manso PH, Silveira VS, Cunha FQ, de Castro M, Carlotti AP. Inflammation, myocardial dysfunction, and mortality in children with septic shock: an observational study. Pediatr Cardiol. 2014 Mar;35(3):463-70. doi: 10.1007/s00246-013-0801-6. Epub 2013 Oct 4. PMID: 24091885; PMCID: PMC7100657. Clique Aqui

Ceravolo GS, Montezano AC, Jordão MT, Akamine EH, Costa TJ, Takano AP, Fernandes DC, Barreto-Chaves ML, Laurindo FR, Tostes RC, Fortes ZB, Chopard RP, Touyz RM, Carvalho MH. An interaction of renin-angiotensin and kallikrein-kinin systems contributes to vascular hypertrophy in angiotensin II-induced hypertension: in vivo and in vitro studies. PLoS One. 2014 Nov 4;9(11):e111117. doi: 10.1371/journal.pone.0111117. PMID: 25369284; PMCID: PMC4219703. Clique Aqui

Correa-Costa M, Braga TT, Felizardo RJ, Andrade-Oliveira V, Perez KR, Cuccovia IM, Hiyane MI, da Silva JS, Câmara NO. Macrophage trafficking as key mediator of adenine-induced kidney injury. Mediators Inflamm. 2014;2014:291024. doi: 10.1155/2014/291024. Epub 2014 Jul 16. PMID: 25132730; PMCID: PMC4124723. Clique Aqui

Cunha LD, Zamboni DS. Recognition of Legionella pneumophila nucleic acids by innate immune receptors. Microbes Infect. 2014 Dec;16(12):985-90. doi: 10.1016/j.micinf.2014.08.008. Epub 2014 Aug 27. PMID: 25172398. Clique Aqui

de Aquino SG, Abdollahi-Roodsaz S, Koenders MI, van de Loo FA, Pruijn GJ, Marijnissen RJ, Walgreen B, Helsen MM, van den Bersselaar LA, de Molon RS, Avila Campos MJ, Cunha FQ, Cirelli JA, van den Berg WB. Periodontal pathogens directly promote autoimmune experimental arthritis by inducing a TLR2- and IL-1-driven Th17 response. J Immunol. 2014 May 1;192(9):4103-11. doi: 10.4049/jimmunol.1301970. Epub 2014 Mar 28. PMID: 24683190. Clique Aqui

de Melo FM, Braga CJ, Pereira FV, Maricato JT, Origassa CS, Souza MF, Melo AC, Silva P, Tomaz SL, Gimenes KP, Scutti JA, Juliano MA, Zamboni DS, Câmara NO, Travassos LR, Ferreira LC, Rodrigues EG. Anti-metastatic immunotherapy based on mucosal administration of flagellin and immunomodulatory P10. Immunol Cell Biol. 2015 Jan;93(1):86-98. doi: 10.1038/icb.2014.74. Epub 2014 Sep 16. PMID:25223833. Clique Aqui

de Melo Leite AC, Teotonio MA, Girão VC, de Lima Pompeu MM, de Melo Nunes R, Cunha TM, Pinto AC, de Queiroz Cunha F, Rocha FA. Meniscal transection rather than excision increases pain behavior and structural damage in experimental osteoarthritis in mice. Osteoarthritis Cartilage. 2014 Nov;22(11):1878-85. doi: 10.1016/j.joca.2014.07.019. Epub 2014 Jul 31. PMID: 25086402. Clique Aqui

de Oliveira KM, da Silva RA, De Rossi A, Fukada SY, Feres M, Nelson-Filho P, da Silva LA. Absence of interleukin 22 affects the oral microbiota and the progression of induced periapical lesions in murine teeth. Int Endod J. 2015 Jan;48(1):46-59. doi: 10.1111/iej.12274. Epub 2014 Apr 4. PMID: 24611911. Clique Aqui

dos Reis Barbosa AL, de Sousa RB, Torres JN, Cunha TM, de Queiroz Cunha F, Soares PM, de Albuquerque Ribeiro R, Vale ML, Souza MH. Colitis generates remote antinociception in rats: the role of the L-arginine/NO/cGMP/PKG/KATP pathway and involvement of cannabinoid and opioid systems. Inflamm Res. 2014 Dec;63(12):969-77. doi: 10.1007/s00011-014-0773-x. Epub 2014 Oct 7. PMID: 25286904. Clique Aqui

Dutra FF, Alves LS, Rodrigues D, Fernandez PL, de Oliveira RB, Golenbock DT, Zamboni DS, Bozza MT. Hemolysis-induced lethality involves inflammasome activation by heme. Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):E4110-8. doi: 10.1073/pnas.1405023111. Epub 2014 Sep 15. PMID: 25225402; PMCID: PMC4191786. Clique Aqui

Ferreira AE, Sisti F, Sônego F, Wang S, Filgueiras LR, Brandt S, Serezani AP, Du H, Cunha FQ, Alves-Filho JC, Serezani CH. PPAR-γ/IL-10 axis inhibits MyD88 expression and ameliorates murine polymicrobial sepsis. J Immunol. 2014 Mar 1;192(5):2357-65. doi: 10.4049/jimmunol.1302375. Epub 2014 Jan 31. PMID: 24489087; PMCID: PMC3943997. Clique Aqui

Figueiredo SA, Vilela FM, da Silva CA, Cunha TM, Dos Santos MH, Fonseca MJ. In vitro and in vivo photoprotective/photochemopreventive potential of Garcinia brasiliensis epicarp extract. J Photochem Photobiol B. 2014 Feb 5;131:65-73. doi: 10.1016/j.jphotobiol.2014.01.004. Epub 2014 Jan 17. PMID: 24491421. Clique Aqui

Gasparoto TH, de Oliveira CE, de Freitas LT, Pinheiro CR, Hori JI, Garlet GP, Cavassani KA, Schillaci R, da Silva JS, Zamboni DS, Campanelli AP. Inflammasome activation is critical to the protective immune response during chemically induced squamous cell carcinoma. PLoS One. 2014 Sep 30;9(9):e107170. doi: 10.1371/journal.pone.0107170. PMID: 25268644; PMCID: PMC4182037. Clique Aqui

Gasparoto TH, de Souza Malaspina TS, Damante JH, de Mello EF Jr, Ikoma MR, Garlet GP, Costa MR, Cavassani KA, da Silva JS, Campanelli AP. Regulatory T cells in the actinic cheilitis. J Oral Pathol Med. 2014 Nov;43(10):754-60. doi: 10.1111/jop.12207. Epub 2014 Jul 24. PMID: 25060152. Clique Aqui

Giachini FR, Leite R, Osmond DA, Lima VV, Inscho EW, Webb RC, Tostes RC. Anti-platelet therapy with clopidogrel prevents endothelial dysfunction and vascular remodeling in aortas from hypertensive rats. PLoS One. 2014 Mar 17;9(3):e91890. doi: 10.1371/journal.pone.0091890. PMID: 24638017; PMCID: PMC3956760. Clique Aqui

Guabiraba R, Besnard AG, Menezes GB, Secher T, Jabir MS, Amaral SS, Braun H, Lima-Junior RC, Ribeiro RA, Cunha FQ, Teixeira MM, Beyaert R, Graham GJ, Liew FY. IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice. Mucosal Immunol. 2014 Sep;7(5):1079-93. doi: 10.1038/mi.2013.124. Epub 2014 Jan 15. PMID: 24424522; PMCID: PMC4077764. Clique Aqui

Gutierrez FR, Pavanelli WR, Medina TS, Silva GK, Mariano FS, Guedes PM, Mineo TW, Rossi MA, Cunha FQ, Silva JS. Haeme oxygenase activity protects the host against excessive cardiac inflammation during experimental Trypanosoma cruzi infection. Microbes Infect. 2014 Jan;16(1):28-39. doi: 10.1016/j.micinf.2013.10.007. Epub 2013 Oct 17. PMID: 24140555. Clique Aqui

Hernandes MS, D'Avila JC, Trevelin SC, Reis PA, Kinjo ER, Lopes LR, Castro-Faria-Neto HC, Cunha FQ, Britto LR, Bozza FA. The role of Nox2-derived ROS in the development of cognitive impairment after sepsis. J Neuroinflammation. 2014 Feb 27;11:36. doi: 10.1186/1742-2094-11-36. PMID: 24571599; PMCID: PMC3974031. Clique Aqui

Ivan AL, Campanini MZ, Martinez RM, Ferreira VS, Steffen VS, Vicentini FT, Vilela FM, Martins FS, Zarpelon AC, Cunha TM, Fonseca MJ, Baracat MM, Georgetti SR, Verri WA Jr, Casagrande R. Pyrrolidine dithiocarbamate inhibits UVB-induced skin inflammation and oxidative stress in hairless mice and exhibits antioxidant activity in vitro. J Photochem Photobiol B. 2014 Sep 5;138:124-33. doi: 10.1016/j.jphotobiol.2014.05.010. Epub 2014 May 27. PMID: 24927233. Clique Aqui

Kwissa M, Nakaya HI, Onlamoon N, Wrammert J, Villinger F, Perng GC, Yoksan S, Pattanapanyasat K, Chokephaibulkit K, Ahmed R, Pulendran B. Dengue virus infection induces expansion of a CD14(+)CD16(+) monocyte population that stimulates plasmablast differentiation. Cell Host Microbe. 2014 Jul 9;16(1):115-27. doi: 10.1016/j.chom.2014.06.001. Epub 2014 Jun 26. PMID: 24981333; PMCID: PMC4116428. Clique Aqui

Leiria LO, Martins MA, Saad MJ. Obesity and asthma: beyond T(H)2 inflammation. Metabolism. 2015 Feb;64(2):172-81. doi: 10.1016/j.metabol.2014.10.002. Epub 2014 Oct 8. PMID: 25458831. Clique Aqui

Lima-Júnior RC, Freitas HC, Wong DV, Wanderley CW, Nunes LG, Leite LL, Miranda SP, Souza MH, Brito GA, Magalhães PJ, Teixeira MM, Cunha FQ, Ribeiro RA. Targeted inhibition of IL-18 attenuates irinotecan-induced intestinal mucositis in mice. Br J Pharmacol. 2014 May;171(9):2335-50. doi: 10.1111/bph.12584. PMID: 24428790; PMCID: PMC3997274. Clique Aqui

Lima VV, Lobato NS, Filgueira FP, Webb RC, Tostes RC, Giachini FR. Vascular O-GlcNAcylation augments reactivity to constrictor stimuli by prolonging phosphorylated levels of the myosin light chain. Braz J Med Biol Res. 2014 Oct;47(10):826-33. doi: 10.1590/1414-431x20144001. Epub 2014 Aug 15. PMID: 25140811; PMCID: PMC4181217. Clique Aqui

Li S, Rouphael N, Duraisingham S, Romero-Steiner S, Presnell S, Davis C, Schmidt DS, Johnson SE, Milton A, Rajam G, Kasturi S, Carlone GM, Quinn C, Chaussabel D, Palucka AK, Mulligan MJ, Ahmed R, Stephens DS, Nakaya HI, Pulendran B. Molecular signatures of antibody responses derived from a systems biology study of five human vaccines. Nat Immunol. 2014 Feb;15(2):195-204. doi: 10.1038/ni.2789. Epub 2013 Dec 15. PMID: 24336226; PMCID: PMC3946932. Clique Aqui

Lopes RA, Neves KB, Pestana CR, Queiroz AL, Zanotto CZ, Chignalia AZ, Valim YM, Silveira LR, Curti C, Tostes RC. Testosterone induces apoptosis in vascular smooth muscle cells via extrinsic apoptotic pathway with mitochondria-generated reactive oxygen species involvement. Am J Physiol Heart Circ Physiol. 2014 Jun 1;306(11):H1485-94. doi: 10.1152/ajpheart.00809.2013. Epub 2014 Mar 21. PMID: 24658017. Clique Aqui

Mascarenhas DP, Pereira MS, Manin GZ, Hori JI, Zamboni DS. Interleukin 1 receptor-driven neutrophil recruitment accounts to MyD88-dependent pulmonary clearance of legionella pneumophila infection in vivo. J Infect Dis. 2015 Jan 15;211(2):322-30. doi: 10.1093/infdis/jiu430. Epub 2014 Aug 7. PMID: 25104770. Clique Aqui

Matsumoto T, Lopes RA, Taguchi K, Kobayashi T, Tostes RC. Linking the beneficial effects of current therapeutic approaches in diabetes to the vascular endothelin system. Life Sci. 2014 Nov 24;118(2):129-35. doi: 10.1016/j.lfs.2013.12.216. Epub 2014 Jan 11. PMID: 24418002. Clique Aqui

Medina-Acosta E, Nakaya HT, Pontillo A, de Souza Campos Fernandes RC. Genetic control of immune response and susceptibility to infectious diseases. Biomed Res Int. 2014;2014:796073. doi: 10.1155/2014/796073. Epub 2014 Feb 13. PMID: 24689057; PMCID: PMC3943192. Clique Aqui

Mendonça MA, Souto FO, Micheli DC, Alves-Filho JC, Cunha FQ, Murta EF, Tavares-Murta BM. Mechanisms affecting neutrophil migration capacity in breast cancer patients before and after chemotherapy. Cancer Chemother Pharmacol. 2014 Feb;73(2):317-24. doi: 10.1007/s00280-013-2348-x. Epub 2013 Nov 21. PMID: 24258454. Clique Aqui

Moriconi A, Cunha TM, Souza GR, Lopes AH, Cunha FQ, Carneiro VL, Pinto LG, Brandolini L, Aramini A, Bizzarri C, Bianchini G, Beccari AR, Fanton M, Bruno A, Costantino G, Bertini R, Galliera E, Locati M, Ferreira SH, Teixeira MM, Allegretti M. Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief. Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16937-42. doi: 10.1073/pnas.1417365111. Epub 2014 Nov 10. PMID: 25385614; PMCID: PMC4250151. Clique Aqui

Mota LM, Cruz BA, Brenol CV, Pollak DF, Pinheiro Gda R, Laurindo IM, Pereira IA, Carvalho JF, Bertolo MB, Pinheiro Mde M, Freitas MV, Silva NA, Louzada-Júnior P, Sampaio-Barros PD, Giorgi RD, Lima RA, Andrade LE. Segurança do uso de terapias biológicas para o tratamento de artrite reumatoide e espondiloartrites [Safe use of biological therapies for the treatment of rheumatoid arthritis and spondyloarthritides]. Rev Bras Reumatol. 2015 May-Jun;55(3):281-309. Portuguese. doi: 10.1016/j.rbr.2014.06.006. Epub 2014 Oct 13. PMID: 26054442. Clique Aqui

Nascimento MS, Carregaro V, Lima-Júnior DS, Costa DL, Ryffel B, Duthie MS, de Jesus A, de Almeida RP, da Silva JS. Interleukin 17A acts synergistically with interferon γ to promote protection against Leishmania infantum infection. J Infect Dis. 2015 Mar 15;211(6):1015-26. doi: 10.1093/infdis/jiu531. Epub 2014 Oct 1. PMID: 25274569. Clique Aqui

Neves KB, Lobato NS, Lopes RA, Filgueira FP, Zanotto CZ, Oliveira AM, Tostes RC. Chemerin reduces vascular nitric oxide/cGMP signalling in rat aorta: a link to vascular dysfunction in obesity? Clin Sci (Lond). 2014 Jul;127(2):111-22. doi: 10.1042/CS20130286. PMID: 24498891. Clique Aqui

Niedbala W, Besnard AG, Nascimento DC, Donate PB, Sonego F, Yip E, Guabiraba R, Chang HD, Fukada SY, Salmond RJ, Schmitt E, Bopp T, Ryffel B, Liew FY. Nitric oxide enhances Th9 cell differentiation and airway inflammation. Nat Commun. 2014 Aug 7;5:4575. doi: 10.1038/ncomms5575. PMID: 25099390; PMCID: PMC4131005. Clique Aqui

Oh JZ, Ravindran R, Chassaing B, Carvalho FA, Maddur MS, Bower M, Hakimpour P, Gill KP, Nakaya HI, Yarovinsky F, Sartor RB, Gewirtz AT, Pulendran B. TLR5-mediated sensing of gut microbiota is necessary for antibody responses to seasonal influenza vaccination. Immunity. 2014 Sep 18;41(3):478-492. doi: 10.1016/j.immuni.2014.08.009. Epub 2014 Sep 11. PMID: 25220212; PMCID: PMC4169736. Clique Aqui

Pereira MS, Rossi MA, Cardoso CR, da Silva JS, Bezerra da Silva LA, Kuga MC, Faria G. Cellular and molecular tissue response to triple antibiotic intracanal dressing. J Endod. 2014 Apr;40(4):499-504. doi: 10.1016/j.joen.2013.10.029. Epub 2014 Jan 8. PMID: 24666899. Clique Aqui

Poo YS, Nakaya H, Gardner J, Larcher T, Schroder WA, Le TT, Major LD, Suhrbier A. CCR2 deficiency promotes exacerbated chronic erosive neutrophil-dominated chikungunya virus arthritis. J Virol. 2014 Jun;88(12):6862-72. doi: 10.1128/JVI.03364-13. Epub 2014 Apr 2. PMID: 24696480; PMCID: PMC4054367. Clique Aqui

Poo YS, Rudd PA, Gardner J, Wilson JA, Larcher T, Colle MA, Le TT, Nakaya HI, Warrilow D, Allcock R, Bielefeldt-Ohmann H, Schroder WA, Khromykh AA, Lopez JA, Suhrbier A. Multiple immune factors are involved in controlling acute and chronic chikungunya virus infection. PLoS Negl Trop Dis. 2014 Dec 4;8(12):e3354. doi: 10.1371/journal.pntd.0003354. PMID: 25474568; PMCID: PMC4256279. Clique Aqui

Prates TP, Taira TM, Holanda MC, Bignardi LA, Salvador SL, Zamboni DS, Cunha FQ, Fukada SY. NOD2 contributes to Porphyromonas gingivalis-induced bone resorption. J Dent Res. 2014 Nov;93(11):1155-62. doi: 10.1177/0022034514551770. Epub 2014 Sep 19. PMID: 25239844; PMCID: PMC4293770. Clique Aqui

Ravindran R, Khan N, Nakaya HI, Li S, Loebbermann J, Maddur MS, Park Y, Jones DP, Chappert P, Davoust J, Weiss DS, Virgin HW, Ron D, Pulendran B. Vaccine activation of the nutrient sensor GCN2 in dendritic cells enhances antigen presentation. Science. 2014 Jan 17;343(6168):313-317. doi: 10.1126/science.1246829. Epub 2013 Dec 5. PMID: 24310610; PMCID: PMC4048998. Clique Aqui

Sacramento LA, Cunha FQ, de Almeida RP, da Silva JS, Carregaro V. Protective role of 5-lipoxigenase during Leishmania infantum infection is associated with Th17 subset. Biomed Res Int. 2014;2014:264270. doi: 10.1155/2014/264270. Epub 2014 Sep 21. PMID: 25309905; PMCID: PMC4189762. Clique Aqui

Saia RS, Mestriner FL, Bertozi G, Cunha FQ, Cárnio EC. Cholecystokinin inhibits inducible nitric oxide synthase expression by lipopolysaccharide-stimulated peritoneal macrophages. Mediators Inflamm. 2014;2014:896029. doi: 10.1155/2014/896029. Epub 2014 Jul 13. PMID: 25125801; PMCID: PMC4122025. Clique Aqui

Sanches SB, Osório FL, Louzada-Junior P, Moraes D, Crippa JA, Martín-Santos R. Association between joint hypermobility and anxiety in Brazilian university students: gender-related differences. J Psychosom Res. 2014 Dec;77(6):558-61. doi: 10.1016/j.jpsychores.2014.08.016. Epub 2014 Sep 3. PMID: 25219975. Clique Aqui

Sanches TL, Cunha LD, Silva GK, Guedes PM, Silva JS, Zamboni DS. The use of a heterogeneously controlled mouse population reveals a significant correlation of acute phase parasitemia with mortality in Chagas disease. PLoS One. 2014 Mar 20;9(3):e91640. doi: 10.1371/journal.pone.0091640. PMID: 24651711; PMCID: PMC3961278. Clique Aqui

Sônego F, Alves-Filho JC, Cunha FQ. Targeting neutrophils in sepsis. Expert Rev Clin Immunol. 2014 Aug;10(8):1019-28. doi: 10.1586/1744666X.2014.922876. Epub 2014 May 28. PMID: 24867165. Clique Aqui

Sônego F, Castanheira FV, Czaikoski PG, Kanashiro A, Souto FO, França RO, Nascimento DC, Freitas A, Spiller F, Cunha LD, Zamboni DS, Alves-Filho JC, Cunha FQ. MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response. PLoS One. 2014 Aug 1;9(8):e103734. doi: 10.1371/journal.pone.0103734. PMID: 25084278; PMCID: PMC4118952. Clique Aqui

Staurengo-Ferrari L, Zarpelon AC, Longhi-Balbinot DT, Marchesi M, Cunha TM, Alves-Filho JC, Cunha FQ, Ferreira SH, Casagrande R, Miranda KM, Verri WA Jr. Nitroxyl inhibits overt pain-like behavior in mice: role of cGMP/PKG/ATP- sensitive potassium channel signaling pathway. Pharmacol Rep. 2014 Aug;66(4):691-8. doi: 10.1016/j.pharep.2014.04.003. Epub 2014 Apr 22. PMID: 24948073; PMCID: PMC4104808. Clique Aqui

Tamashiro LF, Oliveira RD, Oliveira R, Frota ER, Donadi EA, Del-Ben CM, Teixeira AL, Louzada-Junior P. Participation of the neutrophin brain-derived neurotrophic factor in neuropsychiatric systemic lupus erythematosus. Rheumatology (Oxford). 2014 Dec;53(12):2182-90. doi: 10.1093/rheumatology/keu251. Epub 2014 Jun 18. PMID: 24942492. Clique Aqui

Tamim S, Vo DT, Uren PJ, Qiao M, Bindewald E, Kasprzak WK, Shapiro BA, Nakaya HI, Burns SC, Araujo PR, Nakano I, Radek AJ, Kuersten S, Smith AD, Penalva LO. Genomic analyses reveal broad impact of miR-137 on genes associated with malignant transformation and neuronal differentiation in glioblastoma cells. PLoS One. 2014 Jan 22;9(1):e85591. doi: 10.1371/journal.pone.0085591. PMID: 24465609; PMCID: PMC3899048.

Tan Y, Tamayo P, Nakaya H, Pulendran B, Mesirov JP, Haining WN. Gene signatures related to B-cell proliferation predict influenza vaccine-induced antibody response. Eur J Immunol. 2014 Jan;44(1):285-95. doi: 10.1002/eji.201343657. Epub 2013 Nov 29. PMID: 24136404; PMCID: PMC3973429. Clique Aqui

Toller-Kawahisa JE, Vigato-Ferreira IC, Pancoto JA, Mendes-Junior CT, Martinez EZ, Palomino GM, Louzada-Júnior P, Donadi EA, Del Lama JE, Marzocchi-Machado CM. The variant of CD11b, rs1143679 within ITGAM, is associated with systemic lupus erythematosus and clinical manifestations in Brazilian patients. Hum Immunol. 2014 Feb;75(2):119-23. doi: 10.1016/j.humimm.2013.11.013. Epub 2013 Nov 20. PMID: 24269694. Clique Aqui

Trivella DB, Pereira AR, Stein ML, Kasai Y, Byrum T, Valeriote FA, Tantillo DJ, Groll M, Gerwick WH, Moore BS. Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor. Chem Biol. 2014 Jun 19;21(6):782-91. doi: 10.1016/j.chembiol.2014.04.010. Epub 2014 Jun 12. PMID: 24930969; PMCID: PMC4103027. Clique Aqui

Vieira SM, Silva RL, Lemos HP, Amorim RC, Silva EC, Reinach PS, Cunha FQ, Pohlit AM, Cunha TM. Gastro-protective effects of isobrucein B, a quassinoid isolated from Picrolemma sprucei. Fitoterapia. 2014 Jun;95:8-15. doi: 10.1016/j.fitote.2014.02.008. Epub 2014 Mar 1. PMID: 24594240. Clique Aqui

Vigato-Ferreira IC, Toller-Kawahisa JE, Pancoto JA, Mendes-Junior CT, Martinez EZ, Donadi EA, Louzada-Júnior P, Del Lama JE, Marzocchi-Machado CM. FcγRIIa and FcγRIIIb polymorphisms and associations with clinical manifestations in systemic lupus erythematosus patients. Autoimmunity. 2014 Nov;47(7):451-8. doi: 10.3109/08916934.2014.921809. Epub 2014 Jun 4. PMID: 24896836. Clique Aqui

Wanderley CW, Silva CM, Wong DV, Ximenes RM, Morelo DF, Cosker F, Aragão KS, Fernandes C, Palheta-Júnior RC, Havt A, Brito GA, Cunha FQ, Ribeiro RA, Lima-Júnior RC. Bothrops jararacussu snake venom-induces a local inflammatory response in a prostanoid- and neutrophil-dependent manner. Toxicon. 2014 Nov;90:134-47. doi: 10.1016/j.toxicon.2014.08.001. Epub 2014 Aug 12. PMID: 25127849. Clique Aqui

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